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Descriptor English: Enfuvirtide
Descriptor Spanish: Enfuvirtida
Descriptor enfuvirtida
Entry term(s) DP 178
DP-178
DP178
Fuzeon
pentafusida
péptido T20
Scope note: Péptido sintético de 36 aminoácidos que se corresponde con la secuencia de repetición heptádica de la gp41 del VIH-1. Bloquea la fusión del VIH con la célula hospedadora y su entrada en la misma y se usa con otros antirretrovirales para el tratamiento combinado de las INFECCIONES POR VIH y el SIDA.
Descriptor Portuguese: Enfuvirtida
Descriptor French: Enfuvirtide
Entry term(s): DP 178
DP-178
DP178
Fuzeon
Pentafuside
Peptide T20
T20 Peptide
T20, Peptide
Tree number(s): D12.644.541.250
D12.776.543.512.500.330.500
D12.776.964.350.520.330.500
D12.776.964.775.325.164.200.500
D12.776.964.775.562.500.200.500
D12.776.964.970.880.325.164.200.500
D12.776.964.970.880.910.330.500
D23.050.327.520.330.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000077560
Scope note: A synthetic 36-amino acid peptide that corresponds to the heptad repeat sequence of HIV-1 gp41. It blocks HIV cell fusion and viral entry and is used with other anti-retrovirals for combination therapy of HIV INFECTIONS and AIDS.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: HIV Fusion Inhibitors
Registry Number: 19OWO1T3ZE
Public MeSH Note: 2019; ENFUVIRTIDE was indexed under PEPTIDE FRAGMENTS and HIV ENVELOPE PROTEIN GP41 2001-2018; and under ANTI-HIV AGENTS 1997-2000
History Note: 2019 (1997)
DeCS ID: 57685
Unique ID: D000077560
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/06/19
Enfuvirtide - Preferred
Concept UI M0274523
Scope note A synthetic 36-amino acid peptide that corresponds to the heptad repeat sequence of HIV-1 gp41. It blocks HIV cell fusion and viral entry and is used with other anti-retrovirals for combination therapy of HIV INFECTIONS and AIDS.
Preferred term Enfuvirtide
Entry term(s) Pentafuside
DP 178 - Narrower
Concept UI M0476550
Preferred term DP 178
Entry term(s) DP-178
DP178
Fuzeon - Narrower
Concept UI M0446652
Preferred term Fuzeon
T20 Peptide - Narrower
Concept UI M000640944
Preferred term T20 Peptide
Entry term(s) Peptide T20
T20, Peptide



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