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Descriptor English: Histamine H2 Antagonists
Descriptor Spanish: Antagonistas de los Receptores H2 de la Histamina
Descriptor antagonista de los receptores H2 de la histamina
Entry term(s) antagonista H2
antagonistas de los receptores histamínicos H2
antagonistas de receptores de histamina H2
antihistamínico H2
antihistamínicos H2
bloqueador de los receptores H2
bloqueador de los receptores H2 de la histamina
bloqueantes de receptores de histamina H2
Scope note: Fármacos que se unen SELECTIVAMENTE a los receptores H2 de la histamina pero no los activan, de modo que bloquean las acciones de la histamina. Su efecto más importante desde el punto de vista clínico es la inhibición de la secreción ácida en el tratamiento de las úlceras gastrointestinales. También puede verse afectado el músculo liso. Algunos fármacos de esta clase tienen efectos intensos, aunque no bien conocidos, en el sistema nervioso central.
Descriptor Portuguese: Antagonistas dos Receptores H2 da Histamina
Descriptor French: Antihistaminiques des récepteurs H2
Entry term(s): Antagonist, Histamine H2
Antagonists, Histamine H2
Antihistaminics, H2
Blockader, H2 Receptor
Blockaders, H2 Receptor
Blockaders, Histamine H2 Receptor
Blocker, Histamine H2
Blockers, Histamine H2
H2 Antagonist, Histamine
H2 Antagonists, Histamine
H2 Antihistaminics
H2 Blocker, Histamine
H2 Blockers, Histamine
H2 Receptor Blockader
H2 Receptor Blockaders
Histamine H2 Antagonist
Histamine H2 Blocker
Histamine H2 Blockers
Histamine H2 Receptor Antagonist
Histamine H2 Receptor Antagonists
Histamine H2 Receptor Blockader
Histamine H2 Receptor Blockaders
Receptor Antagonists, Histamine H2
Receptor Blockader, H2
Receptor Blockaders, H2
Tree number(s): D27.505.519.625.375.425.425
D27.505.696.577.375.425.425
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D006635
Scope note: Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Public MeSH Note: 95; was HISTAMINE H2 RECEPTOR BLOCKADERS 1977-94
Online Note: use HISTAMINE H2 ANTAGONISTS to search HISTAMINE H2 RECEPTOR BLOCKADERS 1977-94
History Note: 95; was HISTAMINE H2 RECEPTOR BLOCKADERS 1977-94
Entry Version: HISTAMINE H2 ANTAG
Related: Anti-Ulcer Agents MeSH
DeCS ID: 6794
Unique ID: D006635
NLM Classification: QV 157
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1977/01/01
Date of Entry: 1976/05/05
Revision Date: 2020/05/27
Histamine H2 Antagonists - Preferred
Concept UI M0010396
Scope note Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
Preferred term Histamine H2 Antagonists
Entry term(s) Antagonist, Histamine H2
Antagonists, Histamine H2
Antihistaminics, H2
Blockader, H2 Receptor
Blockaders, H2 Receptor
Blockaders, Histamine H2 Receptor
Blocker, Histamine H2
Blockers, Histamine H2
H2 Antagonist, Histamine
H2 Antagonists, Histamine
H2 Antihistaminics
H2 Blocker, Histamine
H2 Blockers, Histamine
H2 Receptor Blockader
H2 Receptor Blockaders
Histamine H2 Antagonist
Histamine H2 Blocker
Histamine H2 Blockers
Histamine H2 Receptor Antagonist
Histamine H2 Receptor Antagonists
Histamine H2 Receptor Blockader
Histamine H2 Receptor Blockaders
Receptor Antagonists, Histamine H2
Receptor Blockader, H2
Receptor Blockaders, H2



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