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Descriptor English: Cleavage And Polyadenylation Specificity Factor
Descriptor Spanish: Factor de Especificidad de Desdoblamiento y Poliadenilación
Descriptor factor de especificidad de la escisión y poliadenilación
Entry term(s) factor de especificidad de desdoblamiento y poliadenilación
Scope note: Proteína de unión al ARN que reconoce la secuencia AAUAAA del ARN en el extremo 3' del MARN. Contiene cuatro subunidades de 30, 73, 100 y 160 kD de tamaño molecular y se combina con el FACTOR DE ESTIMULACIÓN DE DESDOBLAMIENTO para formar un complejo estable con el ARNm que dirige el desdoblamiento en 3' y la reacción de poliadenilación.
Descriptor Portuguese: Fator de Especificidade de Clivagem e Poliadenilação
Descriptor French: Facteur de spécificité de clivage et polyadénylation
Entry term(s): CPSF 100 kDa Subunit
CPSF 160 kDa Subunit
CPSF 30 kDa Subunit
CPSF 30K
CPSF 73 kDa Subunit
CPSF Protein
CPSF-100-kDa Subunit
CPSF-160-kDa Subunit
CPSF-30-kDa Subunit
CPSF-73-kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 100 kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 100-kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 160 kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 160-kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 30 kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 30-kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 73 kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 73-kDa Subunit
Cleavage Polyadenylation Specificity Factor
Cleavage-Polyadenylation Specificity Factor
Subunit, CPSF-100-kDa
Subunit, CPSF-160-kDa
Subunit, CPSF-30-kDa
Subunit, CPSF-73-kDa
Tree number(s): D12.776.157.725.124.240
D12.776.664.962.444.240
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D039223
Scope note: An RNA-binding protein that recognizes the AAUAAA RNA SEQUENCE at the 3' end of MRNA. It contains four subunits of 30, 73, 100 and 160 kDa molecular size and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: RNA-Binding Proteins (1992-2002)
Public MeSH Note: 2003; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR was indexed under RNA-BINDING PROTEINS 1992-2002
History Note: 2003; for CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR use MRNA CLEAVAGE AND POLYADENYLATION FACTORS (NM) 1992-2002
DeCS ID: 37405
Unique ID: D039223
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2003/01/01
Date of Entry: 2002/07/03
Revision Date: 2006/07/05
Cleavage And Polyadenylation Specificity Factor - Preferred
Concept UI M0418575
Scope note An RNA-binding protein that recognizes the AAUAAA RNA SEQUENCE at the 3' end of MRNA. It contains four subunits of 30, 73, 100 and 160 kDa molecular size and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.
Preferred term Cleavage And Polyadenylation Specificity Factor
Entry term(s) CPSF Protein
Cleavage Polyadenylation Specificity Factor
Cleavage-Polyadenylation Specificity Factor
Cleavage And Polyadenylation Specificity Factor, 73-kDa Subunit - Narrower
Concept UI M0418589
Preferred term Cleavage And Polyadenylation Specificity Factor, 73-kDa Subunit
Entry term(s) CPSF 73 kDa Subunit
CPSF-73-kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 73 kDa Subunit
Subunit, CPSF-73-kDa
Cleavage And Polyadenylation Specificity Factor, 30-kDa Subunit - Narrower
Concept UI M0195396
Preferred term Cleavage And Polyadenylation Specificity Factor, 30-kDa Subunit
Entry term(s) CPSF 30 kDa Subunit
CPSF 30K
CPSF-30-kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 30 kDa Subunit
Subunit, CPSF-30-kDa
Cleavage And Polyadenylation Specificity Factor, 100-kDa Subunit - Narrower
Concept UI M0418590
Preferred term Cleavage And Polyadenylation Specificity Factor, 100-kDa Subunit
Entry term(s) CPSF 100 kDa Subunit
CPSF-100-kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 100 kDa Subunit
Subunit, CPSF-100-kDa
Cleavage And Polyadenylation Specificity Factor, 160-kDa Subunit - Narrower
Concept UI M0418591
Preferred term Cleavage And Polyadenylation Specificity Factor, 160-kDa Subunit
Entry term(s) CPSF 160 kDa Subunit
CPSF-160-kDa Subunit
Cleavage And Polyadenylation Specificity Factor, 160 kDa Subunit
Subunit, CPSF-160-kDa



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