DeCS

Descriptor English:

Methysergide

Descriptor Spanish:

Metisergida

Spanish from Spain

Descriptor	metisergida
Entry term(s)	dimetilergometrina metilmetilergonovina
Scope note:	Derivado del cornezuelo del centeno, congénere de la DIETILAMIDA DEL ÁCIDO LISÉRGICO. Antagoniza el efecto de la serotonina en los vasos sanguíneos y en la musculatura lisa gastrointestinal, aunque posee pocas de las propiedades de otros alcaloides del cornezuelo. La metisergida se utiliza profilácticamente en la migraña y otras cefaleas vasculares, y como antagonista de la serotonina en el síndrome carcinoide.

Descriptor Portuguese:

Metisergida

Descriptor French:

Méthysergide

Entry term(s):

Dimaléate de méthysergide
Maléate de méthysergide
UML-491
UML491

Tree number(s):

D03.132.327.287.689
D03.633.400.439.689

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D008784

Scope note:

An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.

Allowable Qualifiers:

AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Pharm Action:

Serotonin Antagonists
Vasoconstrictor Agents

Registry Number:

XZA9HY6Z98

CAS Type 1 Name:

Ergoline-8-carboxamide, 9,10-didehydro-N-(1-(hydroxymethyl)propyl)-1,6-dimethyl-, (8beta(S))-

DeCS ID:

8973

Unique ID:

D008784

Documents indexed in the Virtual Health Library (VHL):

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