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| Descriptor en español: |
Antígenos de Histocompatibilidad Clase II
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| Descriptor en inglés: | Histocompatibility Antigens Class II | ||||||
| Descriptor en portugués: | Antígenos de Histocompatibilidade Classe II | ||||||
| Descriptor en francés: | Antigènes d'histocompatibilité de classe II | ||||||
| Término(s) alternativo(s): |
Antigen, Class II Antigen, I-A Antigen, IA Antigens, Class II Antigens, Ia Antigens, Ia-Like Antigens, Immune Response Antigens, Immune-Associated Antigens, Immune-Response-Associated Class II Antigen Class II Antigens Class II Histocompatibility Antigen Class II Histocompatibility Antigens Class II MHC Proteins Class II Major Histocompatibility Antigen Class II Major Histocompatibility Antigens Class II Major Histocompatibility Molecules I A Antigen I-A Antigen I-A-Antigen IA Antigen Ia Antigens Ia Like Antigens Ia-Like Antigen Ia-Like Antigens Immune Associated Antigens Immune Response Antigens Immune Response Associated Antigens Immune-Associated Antigens Immune-Response-Associated Antigens MHC Class II Molecule MHC Class II Molecules MHC II Molecules MHC II Peptide MHC II Peptides MHC-II Molecules Molecules, MHC-II Peptides, MHC II |
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| Código(s) jeráquico(s): |
D09.400.430.890.509 D12.776.395.550.509 D12.776.543.550.440 D23.050.301.500.400 D23.050.705.552.410 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000949 | ||||||
| Nota de alcance: | Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen. |
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| Nota de indización: | human & animal; see also HLA ANTIGENS & specifics for human |
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| Calificadores permitidos: |
AD administration & dosage AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PO poisoning RE radiation effects TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Indexación anterior: |
HLA Antigens (1975-1980) Histocompatibility Antigens (1973-1980) Isoantigens (1973-1980) |
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| Nota Pública de MeSH: | 1989; see ANTIGENS, IMMUNE RESPONSE 1981-88 |
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| Nota de historia: | 1989 (1973); use ANTIGENS, IMMUNE RESPONSE 1981-88 |
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| Vea también los descriptores: |
Genes, MHC Class II
MeSH | ||||||
| Identificador de DeCS: | 24381 | ||||||
| ID del Descriptor: | D000949 | ||||||
| Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
| Fecha de establecimiento: | 01/01/1981 | ||||||
| Fecha de entrada: | 13/05/1980 | ||||||
| Fecha de revisión: | 06/02/2018 |
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CHEMICALS AND DRUGS
Carbohydrates [D09]Carbohydrates -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Histocompatibility Antigens Class II
- Concepto preferido
Immune-Associated Antigens
- Más amplio
| UI del concepto |
M0001420 |
| Nota de alcance | Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen. |
| Término preferido | Histocompatibility Antigens Class II |
| Término(s) alternativo(s) |
Antigen, Class II Antigen, I-A Antigen, IA Antigens, Class II Antigens, Ia Antigens, Ia-Like Antigens, Immune Response Antigens, Immune-Response-Associated Class II Antigen Class II Antigens Class II Histocompatibility Antigen Class II Histocompatibility Antigens Class II MHC Proteins Class II Major Histocompatibility Antigen Class II Major Histocompatibility Antigens Class II Major Histocompatibility Molecules I A Antigen I-A Antigen I-A-Antigen IA Antigen Ia Antigens Ia Like Antigens Ia-Like Antigen Ia-Like Antigens Immune Response Antigens Immune Response Associated Antigens Immune-Response-Associated Antigens MHC Class II Molecule MHC Class II Molecules MHC II Molecules MHC II Peptide MHC II Peptides MHC-II Molecules Molecules, MHC-II Peptides, MHC II |
| UI del concepto |
M0001421 |
| Término preferido | Immune-Associated Antigens |
| Término(s) alternativo(s) |
Antigens, Immune-Associated Immune Associated Antigens |
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