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| Descriptor en español: |
Alquilantes
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| Descriptor en inglés: | Alkylating Agents | ||||||
| Descriptor en portugués: | Alquilantes | ||||||
| Descriptor en francés: | Agents alcoylants | ||||||
| Término(s) alternativo(s): |
Agent, Alkylating Agents, Alkylating Alkylating Agent Alkylator Alkylators |
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| Código(s) jeráquico(s): |
D27.505.519.124 D27.888.569.035 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000477 | ||||||
| Nota de alcance: | Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. |
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| Calificadores permitidos: |
AD administration & dosage AE adverse effects AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Nota Pública de MeSH: | 66 |
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| Nota de historia: | 66(64) |
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| Identificador de DeCS: | 479 | ||||||
| ID del Descriptor: | D000477 | ||||||
| Clasificación de la NLM: | QV 269 | ||||||
| Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
| Fecha de establecimiento: | 01/01/1966 | ||||||
| Fecha de entrada: | 01/01/1999 | ||||||
| Fecha de revisión: | 27/05/2020 |
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CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses -
CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses
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Alkylating Agents
- Concepto preferido
| UI del concepto |
M0000721 |
| Nota de alcance | Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. |
| Término preferido | Alkylating Agents |
| Término(s) alternativo(s) |
Agent, Alkylating Agents, Alkylating Alkylating Agent Alkylator Alkylators |
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