Pesquisa
Descritor em português: Dinaminas
Descritor em inglês: Dynamins
Descritor em espanhol: Dinaminas
Descritor dinaminas
Termo(s) alternativo(s) dinamina GTPasa-deficiente
Nota de escopo: Familia de GTP fosfohidrolasas de alto peso molecular que tienen una función directa en el transporte vesicular. Se asocian con los haces de MICROTÚBULOS y se cree que producen fuerza mecánica mediante un proceso vinculado a la hidrólisis del GTP. Esta enzima fue clasificada anteriormente como EC 3.6.1.50.
Descritor em francês: Dynamines
Termo(s) alternativo(s): Dephosphin
Dynamin
Dynamin K44A
Dynamin, Alanine44 Substituted With Lysine
Dynamin, GTPase-Deficient
Dynamin, Mutated Form, K44A
GTPase Deficient Dynamin
GTPase-Deficient Dynamin
Código(s) hierárquico(s): D08.811.277.040.330.200
D12.776.220.600.450.200
D12.776.543.990.400
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D034281
Nota de escopo: A family of high molecular weight GTP phosphohydrolases that play a direct role in vesicle transport. They associate with microtubule bundles (MICROTUBULES) and are believed to produce mechanical force via a process linked to GTP hydrolysis. This enzyme was formerly listed as EC 3.6.1.50.
Nota de indexação: general or unspecified; prefer specifics
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Número de registro: EC 3.6.5.5
Indexação Anterior: Ca(2+) Mg(2+)-ATPase (1989-1994)
GTP Phosphohydrolases (1994-2002)
Nota MeSH pública: 2003; DYNAMIN (now DYNAMINS) was indexed under GTP PHOSPHOHYDROLASES 1 1994-2002 & CA(2+) MG(2+)-ATPASE 1989-1993
Nota histórica: 2003; use DYNAMINS (NM) 1989-2002
Identificador DeCS: 37318
ID do descritor: D034281
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/2003
Data de entrada: 03/07/2002
Data de revisão: 30/06/2005
Dynamins - Conceito preferido
Identificador do conceito M0171126
Nota de escopo A family of high molecular weight GTP phosphohydrolases that play a direct role in vesicle transport. They associate with microtubule bundles (MICROTUBULES) and are believed to produce mechanical force via a process linked to GTP hydrolysis. This enzyme was formerly listed as EC 3.6.1.50.
Termo preferido Dynamins
Termo(s) alternativo(s) Dephosphin
Dynamin
GTPase-Deficient Dynamin - Mais específico
Identificador do conceito M0356790
Nota de escopo Dynamins that contain an alanine in position 44 instead of lysine. The amino acid substitution causes the protein to be GTPase-deficient and unable to function normally in the cell. GTPase-deficient dynamins are used experimentally to study dynamin function.
Termo preferido GTPase-Deficient Dynamin
Termo(s) alternativo(s) Dynamin K44A
Dynamin, Alanine44 Substituted With Lysine
Dynamin, GTPase-Deficient
Dynamin, Mutated Form, K44A
GTPase Deficient Dynamin



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