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Descritor em português: Glucosilceramidase
Descritor em inglês: Glucosylceramidase
Descritor em espanhol: Glucosilceramidasa
Descritor glucosilceramidasa
Termo(s) alternativo(s) D-glucosil-N-acilesfingosina glucohidrolasa
beta-glucocerebrosidasa
glucocerebrosidasa
Nota de escopo: Glicosidasa que hidroliza una glucosilceramida para dar lugar a ceramida libre más glucosa. En la ENFERMEDAD DE GAUCHER, la deficiencia de esta enzima conduce a concentraciones anormalmente altas de glucosilceramida en el cerebro. EC 3.2.1.45.
Descritor em francês: Glucosylceramidase
Termo(s) alternativo(s): Acid beta Glucosidase
Acid beta-Glucosidase
Ceramidase, Glucosyl
Glucocerebrosidase
Glucocerebroside beta Glucosidase
Glucocerebroside beta-Glucosidase
Glucosyl Ceramidase
Glucosyl Hydrolase, Glucosylsphingosine
Glucosylceramide beta Glucosidase
Glucosylceramide beta-Glucosidase
Glucosylsphingosine Glucosyl Hydrolase
Hydrolase, Glucosylsphingosine Glucosyl
beta Glucocerebrosidase
beta-Glucocerebrosidase
beta-Glucosidase, Acid
beta-Glucosidase, Glucocerebroside
beta-Glucosidase, Glucosylceramide
Código(s) hierárquico(s): D08.811.277.450.420.412
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D005962
Nota de escopo: A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.
Nota de indexação: /defic: consider also GAUCHER DISEASE
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Número de registro: EC 3.2.1.45
Nome CAS Tipo 1: D-Glucosyl-N-acylsphingosine glucosylhydrolase
Indexação Anterior: Cerebrosides (1970-1974)
Glucose (1970-1974)
Glycoside Hydrolases (1970-1974)
Nota MeSH pública: 91; was see under GLUCOSIDASES 1975-90
Nota histórica: 91(75); was see under GLUCOSIDASES 1975-90
Veja também os descritores: Gaucher Disease MeSH
Identificador DeCS: 6107
ID do descritor: D005962
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1991
Data de entrada: 19/11/1974
Data de revisão: 08/07/2013
Glucosylceramidase - Conceito preferido
Identificador do conceito M0009360
Nota de escopo A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.
Termo preferido Glucosylceramidase
Termo(s) alternativo(s) Acid beta Glucosidase
Acid beta-Glucosidase
Ceramidase, Glucosyl
Glucocerebrosidase
Glucocerebroside beta Glucosidase
Glucocerebroside beta-Glucosidase
Glucosyl Ceramidase
Glucosyl Hydrolase, Glucosylsphingosine
Glucosylceramide beta Glucosidase
Glucosylceramide beta-Glucosidase
Glucosylsphingosine Glucosyl Hydrolase
Hydrolase, Glucosylsphingosine Glucosyl
beta Glucocerebrosidase
beta-Glucocerebrosidase
beta-Glucosidase, Acid
beta-Glucosidase, Glucocerebroside
beta-Glucosidase, Glucosylceramide



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