Search on: TAMOXIFEN 
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Descriptor English:   Tamoxifen 
Descriptor Spanish:   Tamoxifeno 
Descriptor Portuguese:   Tamoxifeno 
Synonyms English:   ICI-46,474
ICI-46474
ICI-47699
Nolvadex
Novaldex
Soltamox
Tamoxifen Citrate
Tomaxithen
Zitazonium
Citrate, Tamoxifen
ICI 46,474
ICI 46474
ICI 47699
ICI46,474
ICI46474
ICI47699  
Tree Number:   D02.455.426.559.389.150.700.900
Definition English:   One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM. 
Pharmacological Action:   Antineoplastic Agents, Hormonal
Bone Density Conservation Agents
Estrogen Antagonists
Selective Estrogen Receptor Modulators
 
History Note English:   78(75); was see under STILBENES 1975-77 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   14010 
Unique Identifier:   D013629 

Occurrence in VHL:
 
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