Pesquisa sobre: MFN=57059 
Descritores Encontrados: 1
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Descritor Inglês:   Inhibitor of Growth Protein 1 
Descritor Espanhol:   Proteína Inhibidora del Crecimiento 1 
Descritor Português:   Proteína 1 Inibidora do Crescimento 
Sinônimos Inglês:   ING-1 Protein
ING1 Protein
p33ING Protein
ING 1 Protein  
Categoria:   D12.644.360.368
D12.776.476.383
D12.776.624.776.503
D12.776.660.494
Definição Inglês:   A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57059 
Identificador Único:   D000076023 

Ocorrência na BVS:
 
MEDLINE    

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