Pesquisa sobre: MFN=57110 
Descritores Encontrados: 1
Mostrando: 1 .. 1  

 1 / 1 DeCS     
Descritor Inglês:   Pre-B-Cell Leukemia Transcription Factor 1 
Descritor Espanhol:   Factor de Transcripción 1 de La Leucemia de Células Pre-B 
Descritor Português:   Fator de Transcrição 1 de Leucemia de Células Pré-B 
Sinônimos Inglês:   PBX1 Homeobox Protein
Pre-B-Cell Leukemia Homeobox 1 Protein
Homeobox Protein, PBX1
Pre B Cell Leukemia Homeobox 1 Protein
Pre B Cell Leukemia Transcription Factor 1  
Categoria:   D12.776.260.400.836
D12.776.624.664.700.163
D12.776.930.712
Definição Inglês:   A TALE-type homeodomain protein and transcription factor that binds the DNA sequence 5'-ATCAATCAA-3'. It forms a heterodimer with MEIS1 TRANSCRIPTION FACTOR and functions as a transcriptional activator of HOMEOBOX PROTEIN NKX-2.5 and ELONGIN A, and as a transcriptional repressor of CDKN2B PROTEIN, in the regulation of developmental and morphogenetic processes such as spleen and limb development. Chromosome translocations involving the PBX1 and TCF3 genes occur in cases of pre-B-cell ACUTE LYMPHOID LEUKEMIA. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   57110 
Identificador Único:   D000075062 

Ocorrência na BVS:
 
MEDLINE    

Similar:

 
DeCS CID-10 LILACS