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Descriptor English: Tyrosine Transaminase
Descriptor Spanish: Tirosina Transaminasa
Descriptor tirosina transaminasa
Entry term(s) tirosina aminotransferasa
Scope note: Enzima que cataliza la conversión de L-TIROSINA y 2-oxoglutarato a 4-hidroxifenilpiruvato y L-GLUTAMATO. Es una proteína con fosfato de piridoxal. La L-FENILALANINA es hidroxilada a L-tirosina. La enzima mitocondrial puede ser idéntica a la ASPARTATO TRANSAMINASA (EC 2.6.1.1.). La deficiencia de esta enzima puede causar la Tirosinemia tipo II (ver TIROSINEMIAS). EC 2.6.1.5.
Descriptor Portuguese: Tirosina Transaminase
Descriptor French: Tyrosine aminotransferase
Entry term(s): Aminotransferase, Tyrosine
Transaminase, Tyrosine
Tyrosine Aminotransferase
Tree number(s): D08.811.913.477.700.900
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D014444
Scope note: An enzyme that catalyzes the conversion of L-TYROSINE and 2-oxoglutarate to 4-hydroxyphenylpyruvate and L-GLUTAMATE. It is a pyridoxal-phosphate protein. L-PHENYLALANINE is hydroxylated to L-tyrosine. The mitochondrial enzyme may be identical with ASPARTATE AMINOTRANSFERASES (EC 2.6.1.1.). Deficiency of this enzyme may cause type II Tyrosinemia (see TYROSINEMIAS). EC 2.6.1.5.
Annotation: /defic: consider also TYROSINEMIAS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.6.1.5
CAS Type 1 Name: L-Tyrosine:2-oxoglutarate aminotransferase
Public MeSH Note: 95; was TYROSINE AMINOTRANSFERASE 1964-94
Online Note: use TYROSINE TRANSAMINASE to search TYROSINE AMINOTRANSFERASE 1966-94 (as Prov 1966-68)
History Note: 95; was TYROSINE AMINOTRANSFERASE 1964-94 (Prov 1964-68)
Related: Tyrosinemias MeSH
DeCS ID: 14843
Unique ID: D014444
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2003/07/09
Tyrosine Transaminase - Preferred
Concept UI M0022204
Scope note An enzyme that catalyzes the conversion of L-TYROSINE and 2-oxoglutarate to 4-hydroxyphenylpyruvate and L-GLUTAMATE. It is a pyridoxal-phosphate protein. L-PHENYLALANINE is hydroxylated to L-tyrosine. The mitochondrial enzyme may be identical with ASPARTATE AMINOTRANSFERASES (EC 2.6.1.1.). Deficiency of this enzyme may cause type II Tyrosinemia (see TYROSINEMIAS). EC 2.6.1.5.
Preferred term Tyrosine Transaminase
Entry term(s) Aminotransferase, Tyrosine
Transaminase, Tyrosine
Tyrosine Aminotransferase



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