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Descriptor English: Dynorphins
Descriptor Spanish: Dinorfinas
Descriptor dinorfinas
Scope note: Clase de péptidos opioides que incluyen la dinorfina A, dinorfina B y fragmentos más pequeños de estos péptidos. Las dinorfinas prefieren los receptores kappa-opioides (RECEPTORES, OPIOIDE, KAPPA) y se ha demostrado que desempeñan un papel como transmisores del sistema nervioso central.
Descriptor Portuguese: Dinorfinas
Descriptor French: Dynorphines
Entry term(s): Dynorphin
Dynorphin (1-17)
Dynorphin A
Dynorphin A (1-17)
Tree number(s): D12.644.400.575.180
D12.776.631.650.575.180
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004399
Scope note: A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Neurotransmitter Agents
Registry Number: 74913-18-1
Previous Indexing: Endorphins (Jul 1977-1984)
Peptides (1966-Jul 1977)
Public MeSH Note: 95; was DYNORPHIN 1985-94
Online Note: use DYNORPHINS to search DYNORPHIN 1985-94
History Note: 95; was DYNORPHIN 1985-94
Related: Receptors, Opioid, kappa MeSH
DeCS ID: 22432
Unique ID: D004399
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1985/01/01
Date of Entry: 1984/05/25
Revision Date: 2015/11/23
Dynorphins - Preferred
Concept UI M0006908
Scope note A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters.
Preferred term Dynorphins
Entry term(s) Dynorphin
Dynorphin (1-17) - Narrower
Concept UI M0006909
Preferred term Dynorphin (1-17)
Entry term(s) Dynorphin A
Dynorphin A (1-17)



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