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Descriptor English: Radioimmunoassay
Descriptor Spanish: Radioinmunoensayo
Descriptor radioinmunoanálisis
Scope note: Análisis cuantitativos clásicos para detectar reacciones antígeno-anticuerpo utilizando una sustancia marcada con radioisótopos (radioligando) para medir directa o indirectamente la unión de la sustancia no marcada a un anticuerpo específico o a otro sistema receptor. Se pueden medir sustancias no inmunogénicas (ejemplo, haptenos) si se acoplan a proteínas transportadoras mayores (p.ej., albúmina sérica humana o gamma-globulina bovina) capaces de inducir la formación de anticuerpos.
Descriptor Portuguese: Radioimunoensaio
Descriptor French: Dosage radioimmunologique
Entry term(s): Radioimmunoassays
Tree number(s): E01.370.384.700
E05.478.566.639
E05.601.470.639
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011863
Scope note: Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.
Annotation: NIM; coord with substance /anal or body fluid qualif but not /immunol; do not confuse with IMMUNORADIOMETRIC ASSAY
Allowable Qualifiers: AE adverse effects
CL classification
EC economics
ES ethics
HI history
IS instrumentation
MO mortality
MT methods
NU nursing
PX psychology
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Previous Indexing: Immunoassay (1966-1967)
Public MeSH Note: 68
History Note: 68
DeCS ID: 22633
Unique ID: D011863
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/23
Radioimmunoassay - Preferred
Concept UI M0018419
Scope note Classic quantitative assay for detection of antigen-antibody reactions using a radioactively labeled substance (radioligand) either directly or indirectly to measure the binding of the unlabeled substance to a specific antibody or other receptor system. Non-immunogenic substances (e.g., haptens) can be measured if coupled to larger carrier proteins (e.g., bovine gamma-globulin or human serum albumin) capable of inducing antibody formation.
Preferred term Radioimmunoassay
Entry term(s) Radioimmunoassays



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