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Descriptor English: Killer Cells, Natural
Descriptor Spanish: Células Asesinas Naturales
Descriptor células asesinas naturales
Entry term(s) células NK
linfocitos citolíticos
linfocitos citolíticos naturales
Scope note: Linfocitos derivados de la médula ósea que poseen propiedades citotóxicas, típicamente dirigidas contra las células alteradas o infectadas por virus. A diferencia de las CÉLULAS T y las CÉLULAS B, las CÉLULAS NK no son específicas de antígenos. La citotoxicidad de las células asesinas naturales viene determinada por la señalización colectiva de una serie de RECEPTORES DE LA SUPERFICIE CELULAR inhibidores y estimuladores. Un subconjunto de LINFOCITOS T, denominadas CÉLULAS T ASESINAS NATURALES, comparten algunas propiedades de este tipo celular.
Descriptor Portuguese: Células Matadoras Naturais
Descriptor French: Cellules tueuses naturelles
Entry term(s): Cell, NK
Cell, Natural Killer
Cells, NK
Cells, Natural Killer
Killer Cell, Natural
NK Cell
NK Cells
Natural Killer Cell
Natural Killer Cells
Tree number(s): A11.118.637.555.567.537
A15.145.229.637.555.567.537
A15.382.490.555.567.537
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007694
Scope note: Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
Annotation: do not confuse with NATURAL KILLER T-CELLS; if subpopulations are discussed, coordinate IM with LYMPHOCYTE SUBSETS (IM)
Allowable Qualifiers: CH chemistry
CL classification
CY cytology
DE drug effects
EN enzymology
IM immunology
ME metabolism
MI microbiology
PA pathology
PH physiology
PS parasitology
RE radiation effects
TR transplantation
UL ultrastructure
VI virology
Previous Indexing: Cytotoxicity, Immunologic (1978-1982)
Immunity, Cellular (1976-1982)
Killer Cells (1978-1982)
Public MeSH Note: 1983
History Note: 1983
Related: Receptors, Natural Killer Cell MeSH
DeCS ID: 23295
Unique ID: D007694
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1983/01/01
Date of Entry: 1982/04/29
Revision Date: 2013/07/09
Killer Cells, Natural - Preferred
Concept UI M0012035
Scope note Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
Preferred term Killer Cells, Natural
Entry term(s) Cell, NK
Cell, Natural Killer
Cells, NK
Cells, Natural Killer
Killer Cell, Natural
NK Cell
NK Cells
Natural Killer Cell
Natural Killer Cells



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