| Descriptor English: | Lymphocyte Activation | ||||||
| Descriptor Spanish: |
Activación de Linfocitos
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| Descriptor Portuguese: | Ativação Linfocitária | ||||||
| Descriptor French: | Activation des lymphocytes | ||||||
| Entry term(s): |
Activation, Lymphocyte Blast Transformation Blastogenesis Lymphoblast Transformation Lymphocyte Stimulation Lymphocyte Transformation Stimulation, Lymphocyte Transformation, Blast Transformation, Lymphoblast Transformation, Lymphocyte |
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| Tree number(s): |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D008213 | ||||||
| Scope note: | Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION. |
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| Annotation: | lymphocyte transformation test goes here but do not index under specific agent inducing transformation unless particularly discussed; do not use for neoplastic transformation of lymphocytes ( = CELL TRANSFORMATION, NEOPLASTIC) or viral transformation of lymphocytes ( = CELL TRANSFORMATION, VIRAL); blast transformation in chronic myelogenous leukemia does not go here: index BLAST CRISIS; DF: LYMPHOCYTE TRANSFORM |
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| Allowable Qualifiers: |
DE drug effects GE genetics IM immunology PH physiology RE radiation effects |
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| Previous Indexing: |
Lymphocytes/immunology (1966-1968) |
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| Public MeSH Note: | 2003; see LYMPHOCYTE TRANSFORMATION 1972-2002; for BLAST TRANSFORMATION see BLAST CRISIS 1987-1992 |
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| History Note: | 2003 (1969); for BLAST TRANSFORMATION use BLAST CRISIS 1987-1992 |
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| Related: |
Blast Crisis
MeSH | ||||||
| DeCS ID: | 23302 | ||||||
| Unique ID: | D008213 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1972/01/01 | ||||||
| Date of Entry: | 1999/01/01 | ||||||
| Revision Date: | 2016/06/23 |
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ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT
Diagnosis [E01]Diagnosis -
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT
Investigative Techniques [E05]Investigative Techniques -
ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT
Investigative Techniques [E05]Investigative Techniques -
PHENOMENA AND PROCESSES
Immune System Phenomena [G12]Immune System Phenomena -
PHENOMENA AND PROCESSES
Immune System Phenomena [G12]Immune System Phenomena
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Lymphocyte Activation
- Preferred
| Concept UI |
M0012805 |
| Scope note | Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION. |
| Preferred term | Lymphocyte Activation |
| Entry term(s) |
Activation, Lymphocyte Blast Transformation Blastogenesis Lymphoblast Transformation Lymphocyte Stimulation Lymphocyte Transformation Stimulation, Lymphocyte Transformation, Blast Transformation, Lymphoblast Transformation, Lymphocyte |
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