| Descriptor English: | Amantadine | ||||
| Descriptor Spanish: | 
                                Amantadina                                        
                                        
                                                                                                                            
                                            
  | ||||
| Descriptor Portuguese: | Amantadina | ||||
| Descriptor French: | Amantadine | ||||
| Entry term(s): | 
                                    1 Aminoadamantane 1-Aminoadamantane AL, Amantadin AZU, Amantadin Adamantylamine Adekin Aman Amanta Amanta HCI AZU Amanta Sulfate AZU Amanta-HCI-AZU Amanta-Sulfate-AZU AmantaHCIAZU AmantaSulfateAZU Amantadin AL Amantadin AZU Amantadin Stada Amantadin neuraxpharm Amantadin ratiopharm Amantadin-neuraxpharm Amantadin-ratiopharm Amantadina Juventus Amantadina Llorente Amantadine Hydrochloride Amantadine Sulfate Amantadinneuraxpharm Amantadinratiopharm Amixx Cerebramed Endantadine Gen Amantadine Gen-Amantadine GenAmantadine Hydrochloride, Amantadine Infecto Flu Infecto-Flu InfectoFlu Infex Juventus, Amantadina Llorente, Amantadina Mantadix Midantan PMS Amantadine PMS-Amantadine PMSAmantadine Stada, Amantadin Sulfate, Amantadine Symadine Symmetrel Viregyt Wiregyt tregor  | 
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| Tree number(s): | 
                                        D02.455.426.100.050.035 | 
                                ||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000547 | ||||
| Scope note: | An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake. | 
                                    ||||
| Allowable Qualifiers: | 
                                                                        AA                                                            analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine  | 
                                            ||||
| Pharm Action: | 
                                                                                                    Antiparkinson Agents Antiviral Agents Dopamine Agents Analgesics, Non-Narcotic  | 
                                    ||||
| Registry Number: | BF4C9Z1J53 | ||||
| CAS Type 1 Name: | Tricyclo(3.3.1.13,7)decan-1-amine | ||||
| Public MeSH Note: | 68 | 
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| History Note: | 68(65) | 
                                                ||||
| DeCS ID: | 23941 | ||||
| Unique ID: | D000547 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 1968/01/01 | ||||
| Date of Entry: | 1999/01/01 | ||||
| Revision Date: | 2016/07/05 | 
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                                        CHEMICALS AND DRUGS
 
Organic Chemicals [D02]Organic Chemicals 
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                        Amantadine                                            
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                        Wiregyt                                            
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                        Amanta                                            
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                        Amanta-HCI-AZU                                            
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                        Amanta-Sulfate-AZU                                            
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                        Amantadin AL                                            
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                        Amantadin Stada                                            
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                        Amantadin-neuraxpharm                                            
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                        Amantadin-ratiopharm                                            
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                        Amantadina Juventus                                            
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                        Amantadina Llorente                                            
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                        Amantadine Hydrochloride                                            
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                        Amantadine Sulfate                                            
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                        Amixx                                            
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                        Cerebramed                                            
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                        Gen-Amantadine                                            
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                        Infecto-Flu                                            
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                        Infex                                            
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                        Midantan                                            
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                        PMS-Amantadine                                            
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                        Symadine                                            
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                        Symmetrel                                            
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                        tregor                                            
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                        Viregyt                                            
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                        Adekin                                            
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                        Aman                                            
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                | Concept UI | 
                                        
                                        M0000847 | 
                                
| Scope note | An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake. | 
| Preferred term | Amantadine | 
| Entry term(s) | 
                                        
                                                                                            1 Aminoadamantane                                                 1-Aminoadamantane Adamantylamine  | 
                                
| Concept UI | 
                                        
                                        M0000851 | 
                                
| Preferred term | Wiregyt | 
| Concept UI | 
                                        
                                        M0432289 | 
                                
| Preferred term | Amanta | 
| Concept UI | 
                                        
                                        M0432290 | 
                                
| Preferred term | Amanta-HCI-AZU | 
| Entry term(s) | 
                                        
                                                                                            Amanta HCI AZU                                                 AmantaHCIAZU  | 
                                
| Concept UI | 
                                        
                                        M0432314 | 
                                
| Preferred term | Amanta-Sulfate-AZU | 
| Entry term(s) | 
                                        
                                                                                            AZU, Amantadin                                                 Amanta Sulfate AZU AmantaSulfateAZU Amantadin AZU  | 
                                
| Concept UI | 
                                        
                                        M0432310 | 
                                
| Preferred term | Amantadin AL | 
| Entry term(s) | 
                                        
                                                                                            AL, Amantadin                                                 | 
                                
| Concept UI | 
                                        
                                        M0432291 | 
                                
| Preferred term | Amantadin Stada | 
| Entry term(s) | 
                                        
                                                                                            Stada, Amantadin                                                 | 
                                
| Concept UI | 
                                        
                                        M0432311 | 
                                
| Preferred term | Amantadin-neuraxpharm | 
| Entry term(s) | 
                                        
                                                                                            Amantadin neuraxpharm                                                 Amantadinneuraxpharm  | 
                                
| Concept UI | 
                                        
                                        M0432292 | 
                                
| Preferred term | Amantadin-ratiopharm | 
| Entry term(s) | 
                                        
                                                                                            Amantadin ratiopharm                                                 Amantadinratiopharm  | 
                                
| Concept UI | 
                                        
                                        M0432293 | 
                                
| Preferred term | Amantadina Juventus | 
| Entry term(s) | 
                                        
                                                                                            Juventus, Amantadina                                                 | 
                                
| Concept UI | 
                                        
                                        M0432294 | 
                                
| Preferred term | Amantadina Llorente | 
| Entry term(s) | 
                                        
                                                                                            Llorente, Amantadina                                                 | 
                                
| Concept UI | 
                                        
                                        M0330750 | 
                                
| Preferred term | Amantadine Hydrochloride | 
| Entry term(s) | 
                                        
                                                                                            Hydrochloride, Amantadine                                                 | 
                                
| Concept UI | 
                                        
                                        M0000848 | 
                                
| Preferred term | Amantadine Sulfate | 
| Entry term(s) | 
                                        
                                                                                            Sulfate, Amantadine                                                 | 
                                
| Concept UI | 
                                        
                                        M0432296 | 
                                
| Preferred term | Amixx | 
| Concept UI | 
                                        
                                        M0432297 | 
                                
| Preferred term | Cerebramed | 
| Concept UI | 
                                        
                                        M0432298 | 
                                
| Preferred term | Gen-Amantadine | 
| Entry term(s) | 
                                        
                                                                                            Gen Amantadine                                                 GenAmantadine  | 
                                
| Concept UI | 
                                        
                                        M0432299 | 
                                
| Preferred term | Infecto-Flu | 
| Entry term(s) | 
                                        
                                                                                            Infecto Flu                                                 InfectoFlu  | 
                                
| Concept UI | 
                                        
                                        M0432312 | 
                                
| Preferred term | Infex | 
| Concept UI | 
                                        
                                        M0370891 | 
                                
| Preferred term | Midantan | 
| Concept UI | 
                                        
                                        M0432300 | 
                                
| Preferred term | PMS-Amantadine | 
| Entry term(s) | 
                                        
                                                                                            PMS Amantadine                                                 PMSAmantadine  | 
                                
| Concept UI | 
                                        
                                        M0432301 | 
                                
| Preferred term | Symadine | 
| Concept UI | 
                                        
                                        M0000849 | 
                                
| Preferred term | Symmetrel | 
| Entry term(s) | 
                                        
                                                                                            Endantadine                                                 Mantadix  | 
                                
| Concept UI | 
                                        
                                        M0432313 | 
                                
| Preferred term | tregor | 
| Concept UI | 
                                        
                                        M0000850 | 
                                
| Preferred term | Viregyt | 
| Concept UI | 
                                        
                                        M0432249 | 
                                
| Preferred term | Adekin | 
| Concept UI | 
                                        
                                        M0432309 | 
                                
| Preferred term | Aman | 
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