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Descriptor English: Carbidopa
Descriptor Spanish: Carbidopa
Descriptor carbidopa
Entry term(s) MK-485
MK-486
metildopahidracina
Scope note: Inhibidor de la DOPA DESCARBOXILASA que previene la conversión de LEVODOPA en dopamina. Se emplea en la ENFERMEDAD DE PARKINSON para reducir los efectos adversos periféricos de la LEVODOPA. Por sí misma no tiene efectos antiparkinsonianos.
Descriptor Portuguese: Carbidopa
Descriptor French: Carbidopa
Entry term(s): Carbidopa, (R)-Isomer
Carbidopa, (S)-Isomer
Lodosin
Lodosyn
MK 485
MK 486
MK-485
MK-486
MK485
MK486
Methyldopahydrazine
Tree number(s): D02.092.311.200.538.200
D02.442.200
D02.455.426.559.389.657.166.175.200.538.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002230
Scope note: An inhibitor of DOPA DECARBOXYLASE that prevents conversion of LEVODOPA to dopamine. It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. It has no anti-parkinson activity by itself.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antiparkinson Agents
Dopamine Agents
Aromatic Amino Acid Decarboxylase Inhibitors
Registry Number: MNX7R8C5VO
CAS Type 1 Name: Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, monohydrate, (S)-
Previous Indexing: Dopa (1972-1974)
Hydrazines (1972-1974)
Methyldopa (1972-1974)
Public MeSH Note: 80; was METHYLDOPAHYDRAZINE see under HYDRAZINES 1975-79
Online Note: use CARBIDOPA to search METHYLDOPAHYDRAZINE 1973-79 (as Prov 1973-74)
History Note: 80; was METHYLDOPAHYDRAZINE see under HYDRAZINES 1975-79; was METHYLDOPAHYDRAZINE 1973-74 (Prov)
DeCS ID: 23960
Unique ID: D002230
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1980/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/06/19
Carbidopa - Preferred
Concept UI M0003345
Scope note An inhibitor of DOPA DECARBOXYLASE that prevents conversion of LEVODOPA to dopamine. It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. It has no anti-parkinson activity by itself.
Preferred term Carbidopa
Entry term(s) Methyldopahydrazine
MK-486 - Narrower
Concept UI M0351196
Preferred term MK-486
Entry term(s) MK 486
MK486
Lodosin - Narrower
Concept UI M0351198
Preferred term Lodosin
Entry term(s) Lodosyn
MK-485 - Narrower
Concept UI M0351197
Preferred term MK-485
Entry term(s) MK 485
MK485
Carbidopa, (S)-Isomer - Related but not broader or narrower
Concept UI M0330920
Preferred term Carbidopa, (S)-Isomer
Carbidopa, (R)-Isomer - Related but not broader or narrower
Concept UI M0330921
Preferred term Carbidopa, (R)-Isomer



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