Search
Descriptor English: Peptide Elongation Factor Tu
Descriptor Spanish: Factor Tu de Elongación Peptídica
Descriptor factor Tu de elongación peptídica
Entry term(s) factor tu de elongación
Scope note: Proteína que se encuentra en bacterias y en las mitocondrias de eucariotas y que entrega aminoacil-ARNt al sitio A del ribosoma. El aminoacil-ARNt se une primero a un complejo de factor Tu de elongación que contiene una molécula de GTP unida. El complejo resultante se une entonces al complejo de iniciación 70S. Simultáneamente, el GTP es hidrolizado y el complejo Tu-GDP es liberado del ribosoma 70S. El complejo Tu-GTP es regenerado por el factor Ts de elongación y el GTP a partir del complejo Tu-GDP.
Descriptor Portuguese: Fator Tu de Elongação de Peptídeos
Descriptor French: Facteur Tu d'élongation de la chaîne peptidique
Entry term(s): EF Tu
EF-Tu
Elongation Factor Tu
Eucaryotic Elongation Factor Tu
Factor Tu, Elongation
Protein Synthesis Elongation Factor Tu
eEF Tu
eEF-Tu
Tree number(s): D08.811.277.040.330.300.100.700
D12.776.157.325.150.700
D12.776.476.338.100.700
D12.776.835.700.350.700
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D010444
Scope note: A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.
Annotation: coordinate with MITOCHONDRIAL PROTEINS or BACTERIAL PROTEINS if pertinent
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.1.-
Previous Indexing: Bacterial Proteins (1966-1972)
Peptide Elongation Factors (1973-1985)
Peptides (1966-1972)
Proteins (1966-1972)
Public MeSH Note: 86
History Note: 86
Entry Version: EFTU
DeCS ID: 27752
Unique ID: D010444
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1986/01/01
Date of Entry: 1985/06/06
Revision Date: 2011/06/24
Peptide Elongation Factor Tu - Preferred
Concept UI M0016221
Scope note A protein found in bacteria and eukaryotic mitochondria which delivers aminoacyl-tRNA's to the A site of the ribosome. The aminoacyl-tRNA is first bound to a complex of elongation factor Tu containing a molecule of bound GTP. The resulting complex is then bound to the 70S initiation complex. Simultaneously the GTP is hydrolyzed and a Tu-GDP complex is released from the 70S ribosome. The Tu-GTP complex is regenerated from the Tu-GDP complex by the Ts elongation factor and GTP.
Preferred term Peptide Elongation Factor Tu
Entry term(s) EF Tu
EF-Tu
Elongation Factor Tu
Factor Tu, Elongation
Protein Synthesis Elongation Factor Tu
Eucaryotic Elongation Factor Tu - Narrower
Concept UI M0016220
Preferred term Eucaryotic Elongation Factor Tu
Entry term(s) eEF Tu
eEF-Tu



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey