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Descriptor English: Peptide Elongation Factor 1
Descriptor Spanish: Factor 1 de Elongación Peptídica
Descriptor factor 1 de elongación peptídica
Entry term(s) EF-1
F-1E
factor 1 alfa de elongación
factor 1 beta de elongación
factor 1 de elongación
factor 1 delta de elongación
factor 1 gamma de elongación
factor de elongación 1
factor de elongación 1 alfa
factor de elongación 1 beta
factor de elongación 1 delta
factor de elongación 1 gamma
Scope note: Proteína con múltiples subunidades que es responsable de la unión dependiente del GTP de los aminoacil-ARNt a los ribosomas eucarióticos. La subunidad alfa (EF-1alfa) se une al aminoacil-ARNt y los transfiere al ribosoma en un proceso vinculado a la hidrólisis del GTP. Las subunidades beta y delta (EF-1beta, EF-1delta) intervienen en la conversión del GDP en GTP. La subunidad gamma (EF-1gamma) es un componente estructural.
Descriptor Portuguese: Fator 1 de Elongação de Peptídeos
Descriptor French: Facteur-1 d'élongation de la chaîne peptidique
Entry term(s): EF 1
EF 1H
EF 1alpha
EF 1beta
EF 1delta
EF 1gamma
EF-1
EF-1H
EF-1alpha
EF-1beta
EF-1delta
EF-1gamma
Elongation Factor 1
Elongation Factor 1alpha
Elongation Factor 1beta
Elongation Factor 1delta
Elongation Factor 1gamma
Tree number(s): D08.811.277.040.330.300.100.101
D12.776.157.325.150.101
D12.776.476.338.100.101
D12.776.835.700.350.101
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020648
Scope note: Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Peptide Elongation Factors (1973-1999)
Public MeSH Note: 2000; ELONGATION FACTOR 1 was indexed under PEPTIDE ELONGATION FACTORS 1980-1999; ELONGATION FACTOR 1GAMMA was indexed under PEPTIDE ELONGATION FACTORS 1994-1999
History Note: 2000; for ELONGATION FACTOR 1 use PEPTIDE ELONGATION FACTOR 1 (NM) 1980-1999; for ELONGATION FACTOR 1GAMMA use PEPTIDE ELONGATION FACTOR 1 (NM) 1994-1999
DeCS ID: 34410
Unique ID: D020648
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/04
Revision Date: 2016/06/28
Peptide Elongation Factor 1 - Preferred
Concept UI M0328220
Scope note Peptide elongation factor 1 is a multisubunit protein that is responsible for the GTP-dependent binding of aminoacyl-tRNAs to eukaryotic ribosomes. The alpha subunit (EF-1alpha) binds aminoacyl-tRNA and transfers it to the ribosome in a process linked to GTP hydrolysis. The beta and delta subunits (EF-1beta, EF-1delta) are involved in exchanging GDP for GTP. The gamma subunit (EF-1gamma) is a structural component.
Preferred term Peptide Elongation Factor 1
Entry term(s) EF 1
EF 1H
EF-1
EF-1H
Elongation Factor 1
Elongation Factor 1gamma - Narrower
Concept UI M0224619
Preferred term Elongation Factor 1gamma
Entry term(s) EF 1gamma
EF-1gamma
Elongation Factor 1delta - Narrower
Concept UI M0088226
Preferred term Elongation Factor 1delta
Entry term(s) EF 1delta
EF-1delta
Elongation Factor 1alpha - Narrower
Concept UI M0088232
Preferred term Elongation Factor 1alpha
Entry term(s) EF 1alpha
EF-1alpha
Elongation Factor 1beta - Narrower
Concept UI M0088233
Preferred term Elongation Factor 1beta
Entry term(s) EF 1beta
EF-1beta



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