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Descriptor English: Chondroitin Lyases
Descriptor Spanish: Condroitín Liasas
Descriptor condroitina liasas
Entry term(s) condroitín AC liasa
condroitín B liasa
condroitín eliminasa
condroitín sulfato liasa
Scope note: Enzimas que catalizan la eliminación de residuos delta-4,5-D-glucuronato de polisacáridos que contienen enlaces 1,4-beta-hexosaminil y 1,3-beta-D-glucuronosil o 1,3-alfa-L-iduronosil, llevando así a cabo la despolimerización. EC 4.2.2.4 actúa sobre el condroitín sulfato A y C, así como sobre dermatán sulfato y lentamente, sobre el hialuronato. EC 4.2.2.5. actúa sobre el condroitín sulfato A y C y también sobre el dermatán sulfato y, lentamente, sobre el hialuronato. EC 4.2.2.5 actua sobre el condroitín sulfato A y C.
Descriptor Portuguese: Condroitina Liases
Descriptor French: Chondroitine lyases
Entry term(s): Chondroitin AC Lyase
Chondroitin B Lyase
Chondroitin Eliminase
Chondroitin Sulfate Lyase
Chondroitinase AC II
Chondroitinase-AC II
Eliminase, Chondroitin
Lyase, Chondroitin AC
Lyase, Chondroitin B
Lyase, Chondroitin Sulfate
Lyases, Chondroitin
Sulfate Lyase, Chondroitin
Tree number(s): D08.811.520.241.700.350.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002808
Scope note: Enzymes which catalyze the elimination of delta-4,5-D-glucuronate residues from polysaccharides containing 1,4-beta-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages thereby bringing about depolymerization. EC 4.2.2.4 acts on chondroitin sulfate A and C as well as on dermatan sulfate and slowly on hyaluronate. EC 4.2.2.5 acts on chondroitin sulfate A and C.
Annotation: do not confuse with CHONDROITIN ABC LYASE
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 4.2.2.-
Previous Indexing: Chondroitin (1970-1975)
Lyases (1970-1974)
Polysaccharide-Lyases (1975)
Public MeSH Note: 91; was see under CHONDROITINASES 1976-90
History Note: 91(76); was see under CHONDROITINASES 1976-90
DeCS ID: 2858
Unique ID: D002808
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1975/08/01
Revision Date: 2003/07/09
Chondroitin Lyases - Preferred
Concept UI M0004313
Scope note Enzymes which catalyze the elimination of delta-4,5-D-glucuronate residues from polysaccharides containing 1,4-beta-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages thereby bringing about depolymerization. EC 4.2.2.4 acts on chondroitin sulfate A and C as well as on dermatan sulfate and slowly on hyaluronate. EC 4.2.2.5 acts on chondroitin sulfate A and C.
Preferred term Chondroitin Lyases
Entry term(s) Lyases, Chondroitin
Chondroitin Eliminase - Narrower
Concept UI M0004312
Preferred term Chondroitin Eliminase
Entry term(s) Eliminase, Chondroitin
Chondroitinase-AC II - Narrower
Concept UI M0004315
Preferred term Chondroitinase-AC II
Entry term(s) Chondroitinase AC II
Chondroitin B Lyase - Narrower
Concept UI M0004311
Preferred term Chondroitin B Lyase
Entry term(s) Lyase, Chondroitin B
Chondroitin Sulfate Lyase - Narrower
Concept UI M0004314
Preferred term Chondroitin Sulfate Lyase
Entry term(s) Chondroitin AC Lyase
Lyase, Chondroitin AC
Lyase, Chondroitin Sulfate
Sulfate Lyase, Chondroitin



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