DeCS

Descriptor English:

Cyclosporine

Descriptor Spanish:

Ciclosporina

Spanish from Spain

Descriptor	ciclosporina
Entry term(s)	ciclosporina A
Scope note:	Undecapéptido cíclico extraído de un extracto de hongos del suelo. Es un poderoso inmunosupresor que tiene una acción específica sobre los linfocitos T. Se emplea para la profilaxis del rechazo del injerto en los trasplantes de órganos y tejidos. (Martindale, The Extra Pharmacopoeia, 30th ed)

Descriptor Portuguese:

Ciclosporina

Descriptor French:

Ciclosporine

Entry term(s):

Ciclosporine A
Cyclosporine
Cyclosporine A
OL 27400
OL-27400
OL27400

Tree number(s):

D04.345.566.235.300
D12.644.641.235.300

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D016572

Scope note:

A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).

Annotation:

a specific drug: do not confuse with CYCLOSPORINS

Allowable Qualifiers:

AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine

Entry Combination:

analogs & derivatives:Cyclosporins

Pharm Action:

Antifungal Agents
Dermatologic Agents
Enzyme Inhibitors
Immunosuppressive Agents
Antirheumatic Agents
Calcineurin Inhibitors

Registry Number:

83HN0GTJ6D

CAS Type 1 Name:

Cyclosporin A

DeCS ID:

30164

Unique ID:

D016572