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Descriptor English: Cyclosporine
Descriptor Spanish: Ciclosporina
Descriptor ciclosporina
Entry term(s) ciclosporina A
Scope note: Undecapéptido cíclico extraído de un extracto de hongos del suelo. Es un poderoso inmunosupresor que tiene una acción específica sobre los linfocitos T. Se emplea para la profilaxis del rechazo del injerto en los trasplantes de órganos y tejidos. (Martindale, The Extra Pharmacopoeia, 30th ed)
Descriptor Portuguese: Ciclosporina
Descriptor French: Ciclosporine
Entry term(s): Ciclosporin
CsA Neoral
CsA-Neoral
CsANeoral
CyA NOF
CyA-NOF
Cyclosporin
Cyclosporin A
Cyclosporine A
Neoral
OL 27 400
OL 27-400
OL 27400
Sandimmun
Sandimmun Neoral
Sandimmune
Tree number(s): D04.345.566.235.300
D12.644.641.235.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016572
Scope note: A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).
Annotation: a specific drug: do not confuse with CYCLOSPORINS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: analogs & derivatives:Cyclosporins
Pharm Action: Antifungal Agents
Dermatologic Agents
Enzyme Inhibitors
Immunosuppressive Agents
Antirheumatic Agents
Calcineurin Inhibitors
Registry Number: 83HN0GTJ6D
CAS Type 1 Name: Cyclosporin A
Previous Indexing: Cyclosporins (1982-1991)
Immunosuppressive Agents (1966-1991)
Peptides (1966-1970)
Peptides, Cyclic (1971-1981)
Public MeSH Note: 92(82); for CYCLOSPORIN A see CYCLOSPORINS 1982-91
History Note: 92; for CYCLOSPORIN A use CYCLOSPORINS 1982-91
DeCS ID: 30164
Unique ID: D016572
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1992/01/01
Date of Entry: 1991/01/08
Revision Date: 2014/06/16
Cyclosporine - Preferred
Concept UI M0025279
Scope note A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).
Preferred term Cyclosporine
Entry term(s) Ciclosporin
Cyclosporin
Cyclosporin A
Cyclosporine A
Neoral - Narrower
Concept UI M0025284
Preferred term Neoral
Sandimmun Neoral - Narrower
Concept UI M0025282
Preferred term Sandimmun Neoral
Entry term(s) CyA NOF
CyA-NOF
Sandimmune - Narrower
Concept UI M0025283
Preferred term Sandimmune
Entry term(s) Sandimmun
CsA-Neoral - Narrower
Concept UI M0025281
Preferred term CsA-Neoral
Entry term(s) CsA Neoral
CsANeoral
OL 27-400 - Narrower
Concept UI M0378530
Preferred term OL 27-400
Entry term(s) OL 27 400
OL 27400



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