Descriptor English: | Glucuronosyltransferase | ||||||
Descriptor Spanish: |
Glucuronosiltransferasa
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Descriptor Portuguese: | Glucuronosiltransferase | ||||||
Descriptor French: | Glucuronosyltransferase | ||||||
Entry term(s): |
17 beta Hydroxysteroid UDP Glucuronosyltransferase 17 beta-Hydroxysteroid UDP-Glucuronosyltransferase 4 Nitrophenol UDP Glucuronosyltransferase 4-Nitrophenol-UDP-Glucuronosyltransferase 7 Hydroxycoumarin UDP Glucuronyltransferase 7-Hydroxycoumarin UDP Glucuronyltransferase Androsterone UDP Glucuronosyltransferase Androsterone UDP-Glucuronosyltransferase Bilirubin UDP Glucuronyltransferase Bilirubin UDP-Glucuronyltransferase Estrogen UDP Glucuronosyltransferase Estrogen UDP-Glucuronosyltransferase Estrone Glucuronyltransferase Glucuronic Transferase Glucuronosyltransferase, UDP Glucuronyl Transferase, UDP Glucuronyltransferase Glucuronyltransferase, 7-Hydroxycoumarin UDP Glucuronyltransferase, Estrone Glucuronyltransferase, Morphine Morphine Glucuronyltransferase Transferase, Glucuronic Transferase, UDP Glucuronyl UDP Glucuronic Acid 3 O beta D Galactosyl D Galactose Glucuronosyltransferase UDP Glucuronosyltransferase UDP Glucuronyl Transferase UDP Glucuronyltransferase, 7-Hydroxycoumarin UDP-Glucuronic Acid 3-O-beta-D-Galactosyl-D-Galactose Glucuronosyltransferase UDP-Glucuronosyltransferase, 17 beta-Hydroxysteroid UDP-Glucuronosyltransferase, Androsterone UDP-Glucuronosyltransferase, Estrogen UDP-Glucuronosyltransferase, p-Nitrophenyl UDP-Glucuronyltransferase, Bilirubin p Nitrophenyl UDP Glucuronosyltransferase p-Nitrophenyl UDP-Glucuronosyltransferase |
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Tree number(s): |
D08.811.913.400.450.480 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D014453 | ||||||
Scope note: | A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of UDPglucuronic acid to a variety of endogenous and exogenous compounds. EC 2.4.1.17. |
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Annotation: | /defic: consider also CRIGLER-NAJJAR SYNDROME & coord with BILIRUBIN /metab (NIM) |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 2.4.1.17 | ||||||
CAS Type 1 Name: | UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) | ||||||
Previous Indexing: |
Hexosyltransferases (1972-1973) Transferases (1966-1971) |
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Public MeSH Note: | 92; was UDP GLUCURONOSYLTRANSFERASE 1975-91 (see under HEXOSYLTRANSFERASES 1975-76) |
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Online Note: | use GLUCURONOSYLTRANSFERASE to search UDP GLUCURONOSYLTRANSFERASE 1973-91 (as Prov 1973-74) |
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History Note: | 92; was UDP GLUCURONOSYLTRANSFERASE 1973-91 (see under HEXOSYLTRANSFERASES 1975-76, Prov 1973-74) |
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DeCS ID: | 30427 | ||||||
Unique ID: | D014453 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 1977/01/01 | ||||||
Date of Entry: | 1999/01/01 | ||||||
Revision Date: | 2003/07/09 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
|
Glucuronosyltransferase
- Preferred
4-Nitrophenol-UDP-Glucuronosyltransferase
- Narrower
7-Hydroxycoumarin UDP Glucuronyltransferase
- Narrower
Androsterone UDP-Glucuronosyltransferase
- Narrower
p-Nitrophenyl UDP-Glucuronosyltransferase
- Narrower
Estrogen UDP-Glucuronosyltransferase
- Narrower
Estrone Glucuronyltransferase
- Narrower
UDP-Glucuronic Acid 3-O-beta-D-Galactosyl-D-Galactose Glucuronosyltransferase
- Related but not broader or narrower
Morphine Glucuronyltransferase
- Narrower
17 beta-Hydroxysteroid UDP-Glucuronosyltransferase
- Narrower
Bilirubin UDP-Glucuronyltransferase
- Narrower
Concept UI |
M0022213 |
Scope note | A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of UDPglucuronic acid to a variety of endogenous and exogenous compounds. EC 2.4.1.17. |
Preferred term | Glucuronosyltransferase |
Entry term(s) |
Glucuronic Transferase Glucuronosyltransferase, UDP Glucuronyl Transferase, UDP Glucuronyltransferase Transferase, Glucuronic Transferase, UDP Glucuronyl UDP Glucuronosyltransferase UDP Glucuronyl Transferase |
Concept UI |
M0022215 |
Preferred term | 4-Nitrophenol-UDP-Glucuronosyltransferase |
Entry term(s) |
4 Nitrophenol UDP Glucuronosyltransferase |
Concept UI |
M0022216 |
Preferred term | 7-Hydroxycoumarin UDP Glucuronyltransferase |
Entry term(s) |
7 Hydroxycoumarin UDP Glucuronyltransferase Glucuronyltransferase, 7-Hydroxycoumarin UDP UDP Glucuronyltransferase, 7-Hydroxycoumarin |
Concept UI |
M0022217 |
Preferred term | Androsterone UDP-Glucuronosyltransferase |
Entry term(s) |
Androsterone UDP Glucuronosyltransferase UDP-Glucuronosyltransferase, Androsterone |
Concept UI |
M0022222 |
Preferred term | p-Nitrophenyl UDP-Glucuronosyltransferase |
Entry term(s) |
UDP-Glucuronosyltransferase, p-Nitrophenyl p Nitrophenyl UDP Glucuronosyltransferase |
Concept UI |
M0022219 |
Preferred term | Estrogen UDP-Glucuronosyltransferase |
Entry term(s) |
Estrogen UDP Glucuronosyltransferase UDP-Glucuronosyltransferase, Estrogen |
Concept UI |
M0022220 |
Preferred term | Estrone Glucuronyltransferase |
Entry term(s) |
Glucuronyltransferase, Estrone |
Concept UI |
M0022223 |
Preferred term | UDP-Glucuronic Acid 3-O-beta-D-Galactosyl-D-Galactose Glucuronosyltransferase |
Entry term(s) |
UDP Glucuronic Acid 3 O beta D Galactosyl D Galactose Glucuronosyltransferase |
Concept UI |
M0022221 |
Preferred term | Morphine Glucuronyltransferase |
Entry term(s) |
Glucuronyltransferase, Morphine |
Concept UI |
M0022214 |
Preferred term | 17 beta-Hydroxysteroid UDP-Glucuronosyltransferase |
Entry term(s) |
17 beta Hydroxysteroid UDP Glucuronosyltransferase UDP-Glucuronosyltransferase, 17 beta-Hydroxysteroid |
Concept UI |
M0022218 |
Preferred term | Bilirubin UDP-Glucuronyltransferase |
Entry term(s) |
Bilirubin UDP Glucuronyltransferase UDP-Glucuronyltransferase, Bilirubin |
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