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Descriptor English: Receptors, Glutamate
Descriptor Spanish: Receptores de Glutamato
Descriptor receptores de glutamato
Entry term(s) receptores de aminoácidos excitadores
Scope note: Proteínas de superficie celular que se unen al glutamato para desencadenar cambios que influyen en el comportamiento de la célula. Entre los receptores de glutamato se incluyen los receptores ionotrópicos (receptores de AMPA, de cainato, y de N-metil-D-aspartato) que controlan directamente los canales iónicos, y los receptores metabotrópicos que actúan a través del sistema de segundos mensajeros. Los receptores de glutamato son los mediadores más comunes de la transmisión sináptica excitatoria rápida del sistema nervioso central. También están relacionados con los mecanismos de la memoria y de diversas enfermedades.
Descriptor Portuguese: Receptores de Glutamato
Descriptor French: Récepteurs au glutamate
Entry term(s): Excitatory Amino Acid Receptor
Excitatory Amino Acid Receptors
Glutamate Receptor
Glutamate Receptors
Receptor, Glutamate
Receptors, Excitatory Amino Acid
Tree number(s): D12.776.543.750.720.200.450
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017470
Scope note: Cell-surface proteins that bind glutamate and trigger changes which influence the behavior of cells. Glutamate receptors include ionotropic receptors (AMPA, kainate, and N-methyl-D-aspartate receptors), which directly control ion channels, and metabotropic receptors which act through second messenger systems. Glutamate receptors are the most common mediators of fast excitatory synaptic transmission in the central nervous system. They have also been implicated in the mechanisms of memory and of many diseases.
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: AD administration & dosage
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Entry Combination: antagonists & inhibitors:Excitatory Amino Acid Antagonists
agonists:Excitatory Amino Acid Agonists
Previous Indexing: Receptors, Drug (1980-1981)
Receptors, Endogenous Substances (1980-1984)
Receptors, Synaptic (1980-1992)
Public MeSH Note: 93; GLUTAMATE RECEPTOR was indexed under RECEPTORS, SYNAPTIC 1980-92, RECEPTORS, ENDOGENOUS SUBSTANCES 1980-84 & RECEPTORS, DRUG 1980-81; EXCITATORY AMINO ACID RECEPTORS & RECEPTORS, EXCITATORY AMINO ACID were see RECEPTORS, AMINO ACID 1993
Online Note: use RECEPTORS, GLUTAMATE (NM) to search GLUTAMATE RECEPTOR 1980-92; use RECEPTORS, AMINO ACID to search EXCITATORY AMINO ACID RECEPTORS & RECEPTORS, EXCITATORY AMINO ACID 1993
History Note: 93; was GLUTAMATE RECEPTOR (NM) 1980-92; EXCITATORY AMINO ACID RECEPTORS & RECEPTORS, EXCITATORY AMINO ACID were see RECEPTORS, AMINO ACID 1993
Entry Version: RECEPT GLUTAMATE
DeCS ID: 30561
Unique ID: D017470
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2018/07/01
Receptors, Glutamate - Preferred
Concept UI M0026504
Scope note Cell-surface proteins that bind glutamate and trigger changes which influence the behavior of cells. Glutamate receptors include ionotropic receptors (AMPA, kainate, and N-methyl-D-aspartate receptors), which directly control ion channels, and metabotropic receptors which act through second messenger systems. Glutamate receptors are the most common mediators of fast excitatory synaptic transmission in the central nervous system. They have also been implicated in the mechanisms of memory and of many diseases.
Preferred term Receptors, Glutamate
Entry term(s) Glutamate Receptor
Glutamate Receptors
Receptor, Glutamate
Excitatory Amino Acid Receptor - Related but not broader or narrower
Concept UI M0026505
Preferred term Excitatory Amino Acid Receptor
Entry term(s) Excitatory Amino Acid Receptors
Receptors, Excitatory Amino Acid



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