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Descriptor English: Prion Diseases
Descriptor Spanish: Enfermedades por Prión
Descriptor enfermedades por priones
Entry term(s) demencias transmisibles
encefalopatías espongiformes transmisibles
Scope note: Grupo de trastornos degenerativos del sistema nervioso en hunanos y animales de origen genético, infeccioso o esporádico que se asocian con PRIONES anormales. Estas enfermedades se caracterizan por conversión de la proteína priónica normal a una configuración anómala por medio de un proceso postranslacional. En humanos, estas afecciones se caracterizan generalmente por DEMENCIA, ATAXIA y un desenlace mortal. Entre las características anatomopatológicas figuran una encefalopatía espongiforme sin signos de inflamación. En la literatura antigua se hace referencia en ocasiones a estas enfermedades como ENFERMEDADES POR VIRUS LENTOS no convencionales. (Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)
Descriptor Portuguese: Doenças Priônicas
Descriptor French: Maladies à prions
Entry term(s): Dementia, Transmissible
Dementias, Transmissible
Disorder, Prion-Induced
Disorders, Prion-Induced
Encephalopathies, Spongiform, Transmissible
Encephalopathies, Transmissible Spongiform
Encephalopathy, Transmissible Spongiform
Human Transmissible Spongiform Encephalopathies, Inherited
Inherited Human Transmissible Spongiform Encephalopathies
Prion Disease
Prion Induced Disorder
Prion Protein Disease
Prion Protein Diseases
Prion-Associated Disorders
Prion-Induced Disorder
Prion-Induced Disorders
Spongiform Encephalopathies, Transmissible
Spongiform Encephalopathy, Transmissible
Transmissible Dementia
Transmissible Dementias
Transmissible Spongiform Encephalopathies
Transmissible Spongiform Encephalopathy
Tree number(s): C01.207.800
C10.228.228.800
C10.574.843
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D017096
Scope note: A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)
Annotation: general or unspecified; prefer specifics
Allowable Qualifiers: BL blood
CF cerebrospinal fluid
CI chemically induced
CL classification
CN congenital
CO complications
DG diagnostic imaging
DH diet therapy
DI diagnosis
DT drug therapy
EC economics
EH ethnology
EM embryology
EN enzymology
EP epidemiology
ET etiology
GE genetics
HI history
IM immunology
ME metabolism
MI microbiology
MO mortality
NU nursing
PA pathology
PC prevention & control
PP physiopathology
PS parasitology
PX psychology
RH rehabilitation
RT radiotherapy
SU surgery
TH therapy
TM transmission
UR urine
VE veterinary
VI virology
Previous Indexing: Slow Virus Diseases (1966-1992)
Public MeSH Note: 1993
History Note: 1993
Entry Version: PRION DIS
DeCS ID: 30599
Unique ID: D017096
NLM Classification: WL 301
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1993/01/01
Date of Entry: 1992/05/22
Revision Date: 2015/06/23
Prion Diseases - Preferred
Concept UI M0025975
Scope note A group of genetic, infectious, or sporadic degenerative human and animal nervous system disorders associated with abnormal PRIONS. These diseases are characterized by conversion of the normal prion protein to an abnormal configuration via a post-translational process. In humans, these conditions generally feature DEMENTIA; ATAXIA; and a fatal outcome. Pathologic features include a spongiform encephalopathy without evidence of inflammation. The older literature occasionally refers to these as unconventional SLOW VIRUS DISEASES. (From Proc Natl Acad Sci USA 1998 Nov 10;95(23):13363-83)
Preferred term Prion Diseases
Entry term(s) Dementia, Transmissible
Dementias, Transmissible
Disorder, Prion-Induced
Disorders, Prion-Induced
Encephalopathies, Spongiform, Transmissible
Encephalopathies, Transmissible Spongiform
Encephalopathy, Transmissible Spongiform
Prion Disease
Prion Induced Disorder
Prion Protein Disease
Prion Protein Diseases
Prion-Associated Disorders
Prion-Induced Disorder
Prion-Induced Disorders
Spongiform Encephalopathies, Transmissible
Spongiform Encephalopathy, Transmissible
Transmissible Dementia
Transmissible Dementias
Transmissible Spongiform Encephalopathies
Transmissible Spongiform Encephalopathy
Human Transmissible Spongiform Encephalopathies, Inherited - Narrower
Concept UI M0335897
Preferred term Human Transmissible Spongiform Encephalopathies, Inherited
Entry term(s) Inherited Human Transmissible Spongiform Encephalopathies



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