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Descriptor English: Receptors, GABA
Descriptor Spanish: Receptores de GABA
Descriptor receptores de GABA
Entry term(s) receptores del ácido gamma-aminobutírico
Scope note: Proteínas de la superficie celular que poseen alta afinidad para unirse al GABA y que desencadenan cambios que influyen en el comportamiento de las células. Los receptores de GABA-A controlan los canales de cloro formados por el propio complejo del receptor. Estos se bloquean por la bicuculina y usualmente tienen sitios moduladores sensibles a las benzodiazepinas y los barbituratos. Los receptores de GABA-B actúan a través de las proteínas G sobre varios sistemas efectores, son insensibles a la bicuculina, y tienen alta afinidad por el L-baclofeno.
Descriptor Portuguese: Receptores de GABA
Descriptor French: Récepteurs GABA
Entry term(s): GABA Receptor
GABA Receptors
Receptor, GABA
Receptor, gamma-Aminobutyric Acid
Receptors, gamma Aminobutyric Acid
Receptors, gamma-Aminobutyric Acid
gamma Aminobutyric Acid Receptor
gamma Aminobutyric Acid Receptors
gamma-Aminobutyric Acid Receptor
gamma-Aminobutyric Acid Receptors
Tree number(s): D12.776.543.750.720.200.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018079
Scope note: Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
Allowable Qualifiers: AD administration & dosage
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Entry Combination: antagonists & inhibitors:GABA Antagonists
agonists:GABA Agonists
Previous Indexing: GABA (1979-1984)
Receptors, Cell Surface (1973-1984)
Receptors, GABA-A (1985-1993)
Public MeSH Note: 94; GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID were see RECEPTORS, GABA-BENZODIAZEPINE 1985-93
Online Note: use RECEPTORS, GABA-A to search GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID 1985-93
History Note: 94; GABA RECEPTORS & RECEPTORS, GAMMA-AMINOBUTYRIC ACID were see RECEPTORS, GABA-BENZODIAZEPINE 1985-93
Entry Version: RECEPT GABA
Related: GABA Plasma Membrane Transport Proteins MeSH
DeCS ID: 31127
Unique ID: D018079
NLM Classification: QU 60
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/06/21
Revision Date: 2005/06/30
Receptors, GABA - Preferred
Concept UI M0027273
Scope note Cell-surface proteins that bind GAMMA-AMINOBUTYRIC ACID with high affinity and trigger changes that influence the behavior of cells. GABA-A receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. GABA-B receptors act through G-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for L-baclofen.
Preferred term Receptors, GABA
Entry term(s) GABA Receptor
GABA Receptors
Receptor, GABA
Receptor, gamma-Aminobutyric Acid
Receptors, gamma Aminobutyric Acid
Receptors, gamma-Aminobutyric Acid
gamma Aminobutyric Acid Receptor
gamma Aminobutyric Acid Receptors
gamma-Aminobutyric Acid Receptor
gamma-Aminobutyric Acid Receptors



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