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Descriptor English: Dopamine Antagonists
Descriptor Spanish: Antagonistas de Dopamina
Descriptor antagonistas dopaminérgicos
Entry term(s) antagonista de la dopamina
antagonista de los receptores de la dopamina
antagonista dopaminérgico
antagonistas de dopamina
antagonistas de receptores de dopamina
antagonistas dopamínicos
bloqueador de dopamina
Scope note: Fármacos que se unen a los RECEPTORES DE DOPAMINA, aunque no los activan, y bloquean en consecuencia las acciones de la dopamina o de agonistas exógenos. Muchos fármacos que se utilizan para tratar trastornos psicóticos (FÁRMACOS ANTIPSICÓTICOS) son antagonistas de la dopamina, aunque sus efectos terapéuticos pueden deberse a ajustes encefálicos a largo plazo más que a los efectos agudos del bloqueo de los receptores de la dopamina. Se han usado los antagonistas de la dopamina en otros marcos clínicos; por ejemplo, se han empleado como ANTIEMÉTICOS en el tratamiento del síndrome de Gilles de la Tourette y del hipo. El bloqueo de los receptores de la dopamina se asocia al SÍNDROME MALIGNO POR NEUROLÉPTICOS.
Descriptor Portuguese: Antagonistas de Dopamina
Descriptor French: Antagonistes de la dopamine
Entry term(s): Antagonist, Dopamine
Antagonist, Dopamine Receptor
Antagonist, Dopaminergic
Antagonists, Dopamine
Antagonists, Dopamine Receptor
Antagonists, Dopaminergic
Blocker, Dopamine
Blockers, Dopamine
Dopamine Antagonist
Dopamine Blocker
Dopamine Blockers
Dopamine Receptor Antagonist
Dopamine Receptor Antagonists
Dopaminergic Antagonist
Dopaminergic Antagonists
Receptor Antagonist, Dopamine
Receptor Antagonists, Dopamine
Tree number(s): D27.505.519.625.150.175
D27.505.696.577.150.175
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018492
Scope note: Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Dopamine/antagonists & inhibitors (1966-1994)
Public MeSH Note: 95
History Note: 95
Entry Version: DOPAMINE ANTAG
DeCS ID: 32275
Unique ID: D018492
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1995/01/01
Date of Entry: 1994/06/01
Revision Date: 2020/05/27
Dopamine Antagonists - Preferred
Concept UI M0027734
Scope note Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.
Preferred term Dopamine Antagonists
Entry term(s) Antagonist, Dopamine
Antagonist, Dopamine Receptor
Antagonist, Dopaminergic
Antagonists, Dopamine
Antagonists, Dopamine Receptor
Antagonists, Dopaminergic
Blocker, Dopamine
Blockers, Dopamine
Dopamine Antagonist
Dopamine Blocker
Dopamine Blockers
Dopamine Receptor Antagonist
Dopamine Receptor Antagonists
Dopaminergic Antagonist
Dopaminergic Antagonists
Receptor Antagonist, Dopamine
Receptor Antagonists, Dopamine



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