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Descriptor English: 2,3-Diphosphoglycerate
Descriptor Spanish: 2,3-Difosfoglicerato
Descriptor 2,3-difosfoglicerato
Entry term(s) 2,3-DPG
2,3-bisfosfoglicerato
ácido 2,3-difosfoglicérico
Scope note: Fosfato orgánico muy aniónico que se halla presente en los hematíes humanos en aproximadamente el mismo cociente molar que la hemoglobina. Se une a la desoxihemoglobina pero no a la forma oxigenada, disminuyendo por lo tanto la afinidad por el oxígeno de la hemoglobina. Es esencial para permitir que la hemoglobina descargue oxígeno en los capilares tisulares. Es también un intermedio en la conversión de 3-fosfoglicerato a 2-fosfoglicerato por la fosfoglicerato mutasa (EC 5.4.2.1). (Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
Descriptor Portuguese: 2,3-Difosfoglicerato
Descriptor French: 2,3-Diphosphate de glycérate
Entry term(s): 2,3 Bisphosphoglycerate
2,3 Diphosphoglycerate
2,3 Diphosphoglyceric Acid
2,3-Bisphosphate, Glycerate
2,3-Bisphosphoglycerate
2,3-DPG
2,3-Diphosphoglycerate, (D)-Isomer
2,3-Diphosphoglyceric Acid
Glycerate 2,3-Bisphosphate
Tree number(s): D02.241.081.844.387.388.175
D02.241.511.902.387.388.175
D02.705.400.140.175
D09.811.366.388.175
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019794
Scope note: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Entry Combination: analogs & derivatives:Diphosphoglyceric Acids
Registry Number: 138-81-8
Previous Indexing: Diphosphoglyceric Acids (1980-1997)
Public MeSH Note: 98; 2,3-DIPHOSPHOGLYCERATE was indexed under DIPHOSPHOGLYCERIC ACIDS 1980-97
History Note: 98; use 2,3-DIPHOSPHOGLYCERATE (NM) 1980-97
DeCS ID: 33399
Unique ID: D019794
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2012/07/03
2,3-Diphosphoglycerate - Preferred
Concept UI M0029370
Scope note A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
Preferred term 2,3-Diphosphoglycerate
Entry term(s) 2,3 Bisphosphoglycerate
2,3 Diphosphoglycerate
2,3-Bisphosphate, Glycerate
2,3-Bisphosphoglycerate
2,3-DPG
Glycerate 2,3-Bisphosphate
2,3-Diphosphoglyceric Acid - Broader
Concept UI M0029371
Preferred term 2,3-Diphosphoglyceric Acid
Entry term(s) 2,3 Diphosphoglyceric Acid
2,3-Diphosphoglycerate, (D)-Isomer - Related but not broader or narrower
Concept UI M0329117
Preferred term 2,3-Diphosphoglycerate, (D)-Isomer



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