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Descriptor English: Rhodamine 123
Descriptor Spanish: Rodamina 123
Descriptor rodamina 123
Scope note: Sonda fluorescente de baja toxicidad que es un sustrato potente para el TRANSPORTADOR DE CASETES DE UNIÓN AL ATP, SUBFAMILIA B, MIEMBRO 1, y para el transportador de eflujo bacteriano multifármaco. Se utiliza para evaluar la bioenergética mitocondrial en células vivas y para medir la actividad de eflujo del TRANSPORTADOR DE CASETES DE UNIÓN AL ATP, SUBFAMILIA B, MIEMBRO 1, en células normales y malignas. (Traducción libre del original: Leukemia 1997;11(7):1124-30)
Descriptor Portuguese: Rodamina 123
Descriptor French: Rhodamine 123
Tree number(s): D03.633.300.953.600.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020112
Scope note: A fluorescent probe with low toxicity which is a potent substrate for ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 and the bacterial multidrug efflux transporter. It is used to assess mitochondrial bioenergetics in living cells and to measure the efflux activity of ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 in both normal and malignant cells. (Leukemia 1997;11(7):1124-30)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Fluorescent Dyes
Registry Number: 1N3CZ14C5O
CAS Type 1 Name: Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride
Previous Indexing: Rhodamines (1982-1998)
Public MeSH Note: 99; RHODAMINE 123 was indexed under RHODAMINES 1982-98
History Note: 99; use RHODAMINE 123 (NM) 1982-98
Related: ATP Binding Cassette Transporter, Subfamily B, Member 1 MeSH
DeCS ID: 33815
Unique ID: D020112
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1999/01/01
Date of Entry: 1998/07/20
Revision Date: 2018/07/13
Rhodamine 123 - Preferred
Concept UI M0029850
Scope note A fluorescent probe with low toxicity which is a potent substrate for ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 and the bacterial multidrug efflux transporter. It is used to assess mitochondrial bioenergetics in living cells and to measure the efflux activity of ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 in both normal and malignant cells. (Leukemia 1997;11(7):1124-30)
Preferred term Rhodamine 123



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