| Descriptor English: | ATP Binding Cassette Transporter, Subfamily B, Member 1 | ||||||
| Descriptor Spanish: |
Miembro 1 de la Subfamilia B de Casetes de Unión a ATP
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| Descriptor Portuguese: | Membro 1 da Subfamília B de Cassetes de Ligação de ATP | ||||||
| Descriptor French: | Glycoprotéine P | ||||||
| Entry term(s): |
1, P-Glycoprotein ABCB1 Protein ABCB1, ATP-Dependent Translocase ATP Binding Cassette Transporter, Sub-Family B, Member 1 ATP Dependent Translocase ABCB1 ATP-Binding Cassette, Sub-Family B, Member 1 ATP-Dependent Translocase ABCB1 Antigen, CD243 CD243 Antigen MDR1 Protein MDR1B Protein Multidrug Resistance Protein 1 P Glycoprotein P Glycoprotein 1 P-Glycoprotein P-Glycoprotein 1 PGY 1 Protein PGY-1 Protein Protein, MDR1B Translocase ABCB1, ATP-Dependent |
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| Tree number(s): |
D09.400.430.890.020.400.153 D12.776.157.530.100.075.063 D12.776.157.530.450.074.500.500.250.125 D12.776.395.550.020.400.153 D12.776.543.550.192.400.153 D12.776.543.585.100.200.125 D12.776.543.585.450.074.500.500.250.125 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D020168 | ||||||
| Scope note: | A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE). |
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| Annotation: | note entry term: ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B is also available |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
P-Glycoprotein (1995-1998) |
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| Public MeSH Note: | 2019; see ATP-BINDING CASSETTE, SUB-FAMILY B, MEMBER 1 2018; see P-GLYCOPROTEIN 1995-2017; ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY B, MEMBER 1 was indexed under P-GLYCOPROTEIN 1995-1998; under CARRIER PROTEINS & MEMBRANE GLYCOPROTEINS 1980-1994; under GLYCOPROTEINS 1980-1987; and under MEMBRANE PROTEINS 1980-1982 |
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| History Note: | 2019 (1995) |
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| Related: |
Drug Resistance, Multiple
MeSH | ||||||
| DeCS ID: | 32100 | ||||||
| Unique ID: | D020168 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 1999/01/01 | ||||||
| Date of Entry: | 1998/07/20 | ||||||
| Revision Date: | 2023/04/25 |
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CHEMICALS AND DRUGS
Carbohydrates [D09]Carbohydrates -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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ATP Binding Cassette Transporter, Subfamily B, Member 1
- Preferred
ATP-Dependent Translocase ABCB1
- Narrower
| Concept UI |
M0029890 |
| Scope note | A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE). |
| Preferred term | ATP Binding Cassette Transporter, Subfamily B, Member 1 |
| Entry term(s) |
ABCB1 Protein ATP Binding Cassette Transporter, Sub-Family B, Member 1 ATP-Binding Cassette, Sub-Family B, Member 1 Antigen, CD243 CD243 Antigen MDR1 Protein Multidrug Resistance Protein 1 P Glycoprotein P-Glycoprotein PGY 1 Protein PGY-1 Protein |
| Concept UI |
M000763856 |
| Preferred term | ATP-Dependent Translocase ABCB1 |
| Entry term(s) |
1, P-Glycoprotein ABCB1, ATP-Dependent Translocase ATP Dependent Translocase ABCB1 MDR1B Protein P Glycoprotein 1 P-Glycoprotein 1 Protein, MDR1B Translocase ABCB1, ATP-Dependent |
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