| Descriptor English: | PPAR alpha | ||||||
| Descriptor Spanish: |
PPAR alfa
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| Descriptor Portuguese: | PPAR alfa | ||||||
| Descriptor French: | Récepteur PPAR alpha | ||||||
| Entry term(s): |
PPARalpha Peroxisome Proliferator Activated Receptor alpha Peroxisome Proliferator-Activated Receptor alpha |
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| Tree number(s): |
D12.776.826.239.500 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D047493 | ||||||
| Scope note: | A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR GAMMA is important to metabolism of LIPIDS. It is the target of FIBRATES to control HYPERLIPIDEMIAS. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Transcription Factors (1993-2004) |
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| Public MeSH Note: | 2005; PPAR ALPHA was indexed under TRANSCRIPTION FACTORS & RECEPTORS, CYTOPLASMIC AND NUCLEAR 1994-2004, and under RECEPTORS, ENDOGENOUS SUBSTANCES 1992-1993 |
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| History Note: | 2005(1992) |
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| DeCS ID: | 38772 | ||||||
| Unique ID: | D047493 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2005/01/01 | ||||||
| Date of Entry: | 2004/07/07 | ||||||
| Revision Date: | 2015/06/23 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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PPAR alpha
- Preferred
| Concept UI |
M0199111 |
| Scope note | A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR GAMMA is important to metabolism of LIPIDS. It is the target of FIBRATES to control HYPERLIPIDEMIAS. |
| Preferred term | PPAR alpha |
| Entry term(s) |
PPARalpha Peroxisome Proliferator Activated Receptor alpha Peroxisome Proliferator-Activated Receptor alpha |
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