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Descriptor English: Receptors, Cytoplasmic and Nuclear
Descriptor Spanish: Receptores Citoplasmáticos y Nucleares
Descriptor receptores citoplásmicos y nucleares
Entry term(s) receptor citoplasmático
receptor nuclear
receptor nuclear de hormonas
receptores citoplasmáticos
receptores citoplasmáticos y nucleares
receptores citoplásmicos de hormonas
receptores citosólicos y nucleares
receptores nucleares
receptores nucleares de hormonas
receptores nucleares y citoplásmicos
Scope note: Proteínas citoplásmicas o nucleares que se unen de manera específica a moléculas señalizadoras y desencadenan cambios que influyen en el comportamiento de las células. Los grupos principales son los receptores de hormonas esteroides (RECEPTORES DE ESTEROIDES), que suelen encontrarse en el citoplasma, y los RECEPTORES DE HORMONAS TIROIDEAS, que habitualmente están en el núcleo. Los receptores, a diferencia de las enzimas, generalmente no catalizan cambios químicos en sus ligandos.
Descriptor Portuguese: Receptores Citoplasmáticos e Nucleares
Descriptor French: Récepteurs cytoplasmiques et nucléaires
Entry term(s): Cytoplasmic Hormone Receptors
Cytoplasmic Receptor
Cytoplasmic Receptors
Cytoplasmic and Nuclear Receptors
Cytosol and Nuclear Receptors
Cytosolic and Nuclear Receptors
Hormone Receptor, Nuclear
Hormone Receptors, Cytoplasmic
Hormone Receptors, Nuclear
Intracellular Membrane Receptors
Membrane Receptors, Intracellular
Nuclear Hormone Receptor
Nuclear Hormone Receptors
Nuclear Receptor
Nuclear Receptors
Nuclear and Cytoplasmic Receptors
Receptor, Cytoplasmic
Receptor, Nuclear
Receptor, Nuclear Hormone
Receptors, Cytoplasmic
Receptors, Cytoplasmic Hormone
Receptors, Cytosol and Nuclear
Receptors, Cytosolic and Nuclear
Receptors, Intracellular Membrane
Receptors, Nuclear
Receptors, Nuclear Hormone
Receptors, Nuclear and Cytoplasmic
Tree number(s): D12.776.826
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D018160
Scope note: Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.
Annotation: general or unspecified; prefer specifics; for hormone receptors, see note at RECEPTORS, CELL SURFACE
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Receptors, Cell Surface (1983-1993)
Public MeSH Note: 94
History Note: 94
Entry Version: RECEPT CYTOPLASMIC NUCLEAR
DeCS ID: 31129
Unique ID: D018160
NLM Classification: QU 55.2
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1994/01/01
Date of Entry: 1993/06/30
Revision Date: 2020/05/27
Receptors, Cytoplasmic and Nuclear - Preferred
Concept UI M0027373
Scope note Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.
Preferred term Receptors, Cytoplasmic and Nuclear
Entry term(s) Cytoplasmic and Nuclear Receptors
Cytosol and Nuclear Receptors
Cytosolic and Nuclear Receptors
Nuclear and Cytoplasmic Receptors
Receptors, Cytosol and Nuclear
Receptors, Cytosolic and Nuclear
Receptors, Nuclear and Cytoplasmic
Receptors, Nuclear - Narrower
Concept UI M0027372
Preferred term Receptors, Nuclear
Entry term(s) Nuclear Receptor
Nuclear Receptors
Receptor, Nuclear
Receptors, Cytoplasmic - Narrower
Concept UI M0027371
Preferred term Receptors, Cytoplasmic
Entry term(s) Cytoplasmic Receptor
Cytoplasmic Receptors
Receptor, Cytoplasmic
Receptors, Intracellular Membrane - Narrower
Concept UI M0536280
Preferred term Receptors, Intracellular Membrane
Entry term(s) Intracellular Membrane Receptors
Membrane Receptors, Intracellular
Hormone Receptors, Cytoplasmic - Narrower
Concept UI M0352724
Preferred term Hormone Receptors, Cytoplasmic
Entry term(s) Cytoplasmic Hormone Receptors
Receptors, Cytoplasmic Hormone
Hormone Receptors, Nuclear - Narrower
Concept UI M0352721
Preferred term Hormone Receptors, Nuclear
Entry term(s) Hormone Receptor, Nuclear
Nuclear Hormone Receptor
Nuclear Hormone Receptors
Receptor, Nuclear Hormone
Receptors, Nuclear Hormone



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