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Descriptor English: Dithiothreitol
Descriptor Spanish: Ditiotreitol
Descriptor ditiotreitol
Scope note: Reactivo frecuentemente utiiizado en estudios bioquímicos como agente protector para prevenir la oxidación de grupos SH (tiol) y para reducir disulfuros a ditioles.
Descriptor Portuguese: Ditiotreitol
Descriptor French: Dithiothréitol
Entry term(s): Cleland Reagent
Cleland's Reagent
Clelands Reagent
Reagent, Cleland
Reagent, Cleland's
Sputolysin
Tree number(s): D02.033.800.196
D02.886.740.224
D09.853.196
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004229
Scope note: A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Registry Number: T8ID5YZU6Y
CAS Type 1 Name: 2,3-Butanediol, 1,4-dimercapto-, (R*,R*)-
Previous Indexing: Alcohols (1966-1971)
Tetroses (1966-1971)
Public MeSH Note: 72
History Note: 72
DeCS ID: 4291
Unique ID: D004229
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1972/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08
Dithiothreitol - Preferred
Concept UI M0006621
Scope note A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols.
Preferred term Dithiothreitol
Entry term(s) Cleland Reagent
Cleland's Reagent
Clelands Reagent
Reagent, Cleland
Reagent, Cleland's
Sputolysin - Narrower
Concept UI M0350696
Preferred term Sputolysin



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