Search
Descriptor English: Pemetrexed
Descriptor Spanish: Pemetrexed
Descriptor pemetrexed
Scope note: ANTINEOPLÁSICO derivado de la guanina que funciona como INHIBIDOR DE LA SÍNTESIS DE ÁCIDOS NUCLEICOS mediante su unión e inhibición de la TIMIDILATO SINTASA.
Descriptor Portuguese: Pemetrexede
Descriptor French: Pémétrexed
Entry term(s): LY-231514
LY231514
Pémétrexed de disodium
Pémétrexed disodique
Tree number(s): D03.633.100.759.758.399.454.650
D12.125.067.625.525
D12.125.119.409.525
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068437
Scope note: A guanine-derived ANTINEOPLASTIC AGENT that functions as a NUCLEIC ACID SYNTHESIS INHIBITOR through its binding to, and inhibition of, THYMIDYLATE SYNTHASE.
Allowable Qualifiers: AA analogues et dérivés
AD administration et posologie
AE effets indésirables
AG agonistes
AI antagonistes et inhibiteurs
AN analyse
BL sang
CF liquide cérébrospinal
CH composition chimique
CL classification
CS synthèse chimique
EC économie
HI histoire
IM immunologie
IP isolement et purification
ME métabolisme
PD pharmacologie
PK pharmacocinétique
PO intoxication
RE effets des radiations
SD ressources et distribution
ST normes
TO toxicité
TU usage thérapeutique
UR urine
Pharm Action: Antineoplastic Agents
Enzyme Inhibitors
Folic Acid Antagonists
Nucleic Acid Synthesis Inhibitors
Registry Number: 04Q9AIZ7NO
CAS Type 1 Name: L-Glutamic acid, N-(4-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-
DeCS ID: 55935
Unique ID: D000068437
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2016/05/31
Pémétrexed - Preferred
Concept UI M0227083
Preferred term Pémétrexed
Pémétrexed de disodium - Narrower
Concept UI M000603406
Preferred term Pémétrexed de disodium
Entry term(s) Pémétrexed disodique
LY-231514 - Narrower
Concept UI M0227084
Preferred term LY-231514
Entry term(s) LY231514



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey