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Descriptor English: Fluorouracil
Descriptor Spanish: Fluorouracilo
Descriptor fluorouracilo
Scope note: Análogo de la pirimidina que actúa como antimetabolito antineoplásico. Interfiere con la síntesis del ADN bloqueando la conversión por la TIMIDILATO SINTETASA del ácido desoxiuridílico a ácido timidílico.
Descriptor Portuguese: Fluoruracila
Descriptor French: Fluorouracil
Entry term(s): 5 FU Lederle
5 FU Medac
5 Fluorouracil
5 Fluorouracil Biosyn
5 HU Hexal
5-FU
5-FU Lederle
5-FU Medac
5-Fluorouracil
5-Fluorouracil-Biosyn
5-HU Hexal
5FU
Adrucil
Carac
Dakota, Fluorouracile
Efudex
Efudix
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoroplex
Fluorouracil GRY
Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt
Fluorouracil-GRY
Fluorouracile Dakota
Fluorouracilo Ferrer Far
Fluoruracil
Fluracedyl
Flurodex
Haemato FU
Haemato-FU
Neofluor
Onkofluor
Ribofluor
Tree number(s): D03.383.742.698.875.404
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D005472
Scope note: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites
Antimetabolites, Antineoplastic
Immunosuppressive Agents
Registry Number: U3P01618RT
CAS Type 1 Name: 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-
DeCS ID: 5602
Unique ID: D005472
NLM Classification: QV 269
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2017/05/24
Fluorouracil - Preferred
Concept UI M0008631
Scope note A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
Preferred term Fluorouracil
Entry term(s) 5 Fluorouracil
5-FU
5-Fluorouracil
5FU
Fluoruracil
5-FU Lederle - Narrower
Concept UI M0478646
Preferred term 5-FU Lederle
Entry term(s) 5 FU Lederle
5-FU Medac - Narrower
Concept UI M0478647
Preferred term 5-FU Medac
Entry term(s) 5 FU Medac
5-HU Hexal - Narrower
Concept UI M0478645
Preferred term 5-HU Hexal
Entry term(s) 5 HU Hexal
Adrucil - Narrower
Concept UI M0008633
Preferred term Adrucil
Carac - Narrower
Concept UI M0478643
Preferred term Carac
Efudix - Narrower
Concept UI M0008632
Preferred term Efudix
Entry term(s) Efudex
Fluoro Uracile ICN
Fluoro-Uracile ICN
Fluoroplex - Narrower
Concept UI M0008634
Preferred term Fluoroplex
Entry term(s) Flurodex
Fluorouracil Mononitrate - Narrower
Concept UI M0330274
Preferred term Fluorouracil Mononitrate
Fluorouracil Monopotassium Salt - Narrower
Concept UI M0330275
Preferred term Fluorouracil Monopotassium Salt
Fluorouracil Monosodium Salt - Narrower
Concept UI M0330271
Preferred term Fluorouracil Monosodium Salt
Fluorouracil Potassium Salt - Narrower
Concept UI M0330273
Preferred term Fluorouracil Potassium Salt
Fluorouracil-GRY - Narrower
Concept UI M0478648
Preferred term Fluorouracil-GRY
Entry term(s) Fluorouracil GRY
Fluorouracile Dakota - Narrower
Concept UI M0478650
Preferred term Fluorouracile Dakota
Entry term(s) Dakota, Fluorouracile
Fluorouracilo Ferrer Far - Narrower
Concept UI M0478649
Preferred term Fluorouracilo Ferrer Far
Fluracedyl - Narrower
Concept UI M0478655
Preferred term Fluracedyl
Haemato-FU - Narrower
Concept UI M0478651
Preferred term Haemato-FU
Entry term(s) Haemato FU
Neofluor - Narrower
Concept UI M0478652
Preferred term Neofluor
Onkofluor - Narrower
Concept UI M0478653
Preferred term Onkofluor
Ribofluor - Narrower
Concept UI M0478654
Preferred term Ribofluor
5-Fluorouracil-Biosyn - Narrower
Concept UI M0478644
Preferred term 5-Fluorouracil-Biosyn
Entry term(s) 5 Fluorouracil Biosyn



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