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Descriptor English: Site-Specific DNA-Methyltransferase (Cytosine-N4-Specific)
Descriptor Spanish: Metiltransferasa de ADN de Sitio Específico (Citosina N4 Específica)
Descriptor ADN-metiltransferasa específica del sitio (específica del grupo N4 de la citosina)
Entry term(s) ADN-metiltransferasa específica del sitio (específica de la citosina-N(4))
DNA-metiltransferasa específica del sitio (específica del grupo N4 de la citosina)
Scope note: ADN metiltransferasa que cataliza la transferencia de un grupo metilo de la S-ADENOSILMETIONINA al grupo NH2 exocíclico en la posición 4 de la CITOSINA.
Descriptor Portuguese: DNA-Metiltransferase Sítio-Específica (Citosina N4-Específica)
Descriptor French: Site-Specific DNA-Methyltransferase (Cytosine-N(4)-Specific)
Entry term(s): N(4)-Cytosine-Specific DNA Methylase
Site-Specific DNA-Methyltransferase (Cytosine-N(4)-Specific)
Tree number(s): D08.811.913.555.500.350.100.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D057265
Scope note: A DNA-methyltransferase that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the exocyclic NH2 group at the 4 position of CYTOSINE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.1.1.113
Previous Indexing: DNA-Cytosine Methylases (1988-2009)
Public MeSH Note: 2020; was SITE-SPECIFIC DNA-METHYLTRANSFERASE (CYTOSINE-N(4)-SPECIFIC) 2010-2019
History Note: 2020 (2010)
DeCS ID: 53612
Unique ID: D057265
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2020/06/09
Site-Specific DNA-Methyltransferase (Cytosine-N4-Specific) - Preferred
Concept UI M0535484
Scope note A DNA-methyltransferase that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the exocyclic NH2 group at the 4 position of CYTOSINE.
Preferred term Site-Specific DNA-Methyltransferase (Cytosine-N4-Specific)
Entry term(s) N(4)-Cytosine-Specific DNA Methylase
Site-Specific DNA-Methyltransferase (Cytosine-N(4)-Specific)



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