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Descriptor en español: Sistema de Señalización de MAP Quinasas
Descriptor en inglés: MAP Kinase Signaling System
Descriptor en portugués: Sistema de Sinalização das MAP Quinases
Descriptor en francés: Système de signalisation des MAP kinases
Término(s) alternativo(s): Cascade, MAP Kinase
ERK Pathway
ERK Pathways
ERK Signal Tranduction Pathway
ERK1 2 Pathway
ERK1 and ERK2 Pathway
ERK1-2 Pathway
ERK1-2 Pathways
JNK Pathway
JNK Pathways
JNK Signaling Pathway
JNK Signaling Pathways
Kinase Cascade, MAP
Kinase Pathway, p38
Kinase Pathways, p38
MAP Kinase Cascade
MAP Kinase Cascades
MAP Kinase Module
MAP Kinase Modules
MAP Kinase Signaling Cascades
MAP Kinase Signaling Pathways
MEK ERK Pathway
MEK-ERK Pathway
MEK-ERK Pathways
Module, MAP Kinase
Pathway, ERK
Pathway, ERK1-2
Pathway, JNK
Pathway, JNK Signaling
Pathway, MEK-ERK
Pathway, p38 Kinase
Pathways, ERK
Pathways, ERK1-2
Pathways, JNK
Pathways, JNK Signaling
Pathways, MEK-ERK
Pathways, p38 Kinase
Signaling Pathway, JNK
Signaling Pathways, JNK
p38 Kinase Pathway
p38 Kinase Pathways
p38 Kinase Signaling Pathway
Código(s) jeráquico(s): G02.111.820.560
G03.493.560
G04.835.560
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D020935
Nota de alcance: An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade.
Calificadores permitidos: DE drug effects
GE genetics
IM immunology
PH physiology
RE radiation effects
Indexación anterior: Ca(2+)-Calmodulin Dependent Protein Kinase (1994-1999)
Protein Kinases (1989-1999)
Protein-Serine-Threonine Kinases (1993-1999)
Protein-Tyrosine Kinase (1989-1999)
Nota Pública de MeSH: 2000
Nota de historia: 2000
Vea también los descriptores: MAP Kinase Kinase Kinases MeSH
Mitogen-Activated Protein Kinase Kinases MeSH
Mitogen-Activated Protein Kinases MeSH
Identificador de DeCS: 34468
ID del Descriptor: D020935
Documentos indizados en la Biblioteca Virtual de Salud (BVS): Haga clic aquí para acceder a los documentos de la BVS
Fecha de establecimiento: 01/01/2000
Fecha de entrada: 05/11/1999
Fecha de revisión: 23/06/2016
MAP Kinase Signaling System - Concepto preferido
UI del concepto M0328035
Nota de alcance An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade.
Término preferido MAP Kinase Signaling System
ERK1-2 Pathway - Relacionado pero no más amplio ni más estrecho
UI del concepto M0555312
Término preferido ERK1-2 Pathway
Término(s) alternativo(s) ERK1 2 Pathway
ERK1 and ERK2 Pathway
ERK1-2 Pathways
Pathway, ERK1-2
Pathways, ERK1-2
p38 Kinase Pathway - Más estrecho
UI del concepto M0557375
Término preferido p38 Kinase Pathway
Término(s) alternativo(s) Kinase Pathway, p38
Kinase Pathways, p38
Pathway, p38 Kinase
Pathways, p38 Kinase
p38 Kinase Pathways
p38 Kinase Signaling Pathway
MAP Kinase Cascade - Más estrecho
UI del concepto M0331442
Término preferido MAP Kinase Cascade
Término(s) alternativo(s) Cascade, MAP Kinase
Kinase Cascade, MAP
MAP Kinase Cascades
MAP Kinase Module
MAP Kinase Modules
MAP Kinase Signaling Cascades
Module, MAP Kinase
MAP Kinase Signaling Pathways - Relacionado pero no más amplio ni más estrecho
UI del concepto M0331445
Término preferido MAP Kinase Signaling Pathways
MEK-ERK Pathway - Más estrecho
UI del concepto M0556022
Término preferido MEK-ERK Pathway
Término(s) alternativo(s) MEK ERK Pathway
MEK-ERK Pathways
Pathway, MEK-ERK
Pathways, MEK-ERK
ERK Signal Tranduction Pathway - Más estrecho
UI del concepto M0556021
Término preferido ERK Signal Tranduction Pathway
Término(s) alternativo(s) ERK Pathway
ERK Pathways
Pathway, ERK
Pathways, ERK
JNK Pathway - Más estrecho
UI del concepto M0557374
Término preferido JNK Pathway
Término(s) alternativo(s) JNK Pathways
JNK Signaling Pathway
JNK Signaling Pathways
Pathway, JNK
Pathway, JNK Signaling
Pathways, JNK
Pathways, JNK Signaling
Signaling Pathway, JNK
Signaling Pathways, JNK



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