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Descriptor en español: Carboxipeptidasa B2
Descriptor carboxipeptidasa B2
Término(s) alternativo(s) arginina carboxipeptidasa
carboxipeptidasa U
inhibidor de la fibrinolisis activable por la trombina
Nota de alcance: Carboxipeptidasa que elimina la lisina o la arginina C-terminal de péptidos y proteínas. Se libera carboxipeptidasa B2 (CPB2) a la circulación como proenzima que se activa por el complejo TROMBINA-TROMBOMODULINA. La CPB2 activada está implicada en la modulación de una variedad de procesos al desdoblar e inactivar diversas proteínas y péptidos circulantes que son sus substratos que incluyen la FIBRINA, CININAS y ANAFILATOXINAS.
Descriptor en inglés: Carboxypeptidase B2
Descriptor en portugués: Carboxipeptidase B2
Descriptor en francés: Carboxypeptidase B2
Término(s) alternativo(s): Arginine Carboxypeptidase
Carboxypeptidase B2, Plasma
Carboxypeptidase R
Carboxypeptidase U
Plasma Carboxypeptidase B2
Plasma Procarboxypeptidase B
Procarboxypeptidase U
Thrombin Activatable Fibrinolysis Inhibitor
Thrombin-Activatable Fibrinolysis Inhibitor
Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
Código(s) jeráquico(s): D08.811.277.656.350.245.125
D08.811.277.656.350.555.225
D08.811.277.656.675.555.225
D08.811.277.656.837.092
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D025901
Nota de alcance: A carboxypeptidase that removes C-terminal lysine or arginine from peptides and proteins. Carboxypeptidase B2 (CPB2) is released into the circulation as a proenzyme which is activated by the THROMBIN-THROMBOMODULIN complex. Activated CPB2 is involved in modulating a variety of processes by cleaving and inactivating various circulating proteins and peptides that are its substrates including FIBRIN; KININS; and ANAPHYLATOXINS.
Calificadores permitidos: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Número de registro: EC 3.4.17.20
Indexación anterior: Carboxypeptidases (1979-2001)
Lysine Carboxypeptidase (1994-2001)
Nota Pública de MeSH: 2015; see CARBOXYPEPTIDASE U 2002-2014; CARBOXYPEPTIDASE U (NM) was indexed under CARBOXYPEPTIDASES 1994-2001; for ARGININE CARBOXYPEPTIDASE see LYSINE CARBOXYPEPTIDASE 1997-2001
Nota de historia: 2015 (2002); use CARBOXYPEPTIDASE U (NM) 1994-2001 and LYSINE CARBOXYPEPTIDASE 1997-2001
Identificador de DeCS: 36082
ID del Descriptor: D025901
Documentos indizados en la Biblioteca Virtual de Salud (BVS): Haga clic aquí para acceder a los documentos de la BVS
Fecha de establecimiento: 01/01/2002
Fecha de entrada: 25/07/2001
Fecha de revisión: 06/06/2014
Carboxypeptidase B2 - Concepto preferido
UI del concepto M0376430
Nota de alcance A carboxypeptidase that removes C-terminal lysine or arginine from peptides and proteins. Carboxypeptidase B2 (CPB2) is released into the circulation as a proenzyme which is activated by the THROMBIN-THROMBOMODULIN complex. Activated CPB2 is involved in modulating a variety of processes by cleaving and inactivating various circulating proteins and peptides that are its substrates including FIBRIN; KININS; and ANAPHYLATOXINS.
Término preferido Carboxypeptidase B2
Término(s) alternativo(s) Arginine Carboxypeptidase
Carboxypeptidase B2, Plasma
Carboxypeptidase R
Carboxypeptidase U
Plasma Carboxypeptidase B2
Thrombin Activatable Fibrinolysis Inhibitor
Thrombin-Activatable Fibrinolysis Inhibitor
Thrombin-Activatable Fibrinolysis Inhibitor (TAFI)
Procarboxypeptidase U - Relacionado pero no más amplio ni más estrecho
UI del concepto M0368256
Término preferido Procarboxypeptidase U
Término(s) alternativo(s) Plasma Procarboxypeptidase B



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