Ha seleccionado la visión en Inglés
Descriptor en español: |
MicroARNs
| ||||||
Descriptor en inglés: | MicroRNAs | ||||||
Descriptor en portugués: | MicroRNAs | ||||||
Descriptor en francés: | microARN | ||||||
Término(s) alternativo(s): |
Micro RNA MicroRNA MicroRNA, Primary Primary MicroRNA Primary miRNA RNA, Micro RNA, Small Temporal Small Temporal RNA Temporal RNA, Small miRNA miRNA, Primary miRNAs pre miRNA pre-miRNA pri miRNA pri-miRNA stRNA |
||||||
Código(s) jeráquico(s): |
D13.150.650.319 D13.444.735.150.319 D13.444.735.790.552.500 |
||||||
Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D035683 | ||||||
Nota de alcance: | Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing. |
||||||
Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
||||||
Indexación anterior: |
RNA, Antisense (2001-2002) RNA, Untranslated (2001-2002) |
||||||
Nota Pública de MeSH: | 2003; MICRORNAS was indexed under RNA, UNTRANSLATED and RNA, ANTISENSE 2001-2002 |
||||||
Nota de historia: | 2003; use MICRORNAS (NM) 2001-2002 |
||||||
Vea también los descriptores: |
RNA, Small Interfering
MeSH | ||||||
Identificador de DeCS: | 37535 | ||||||
ID del Descriptor: | D035683 | ||||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
Fecha de establecimiento: | 01/01/2003 | ||||||
Fecha de entrada: | 03/07/2002 | ||||||
Fecha de revisión: | 09/07/2013 |
|
MicroRNAs
- Concepto preferido
Primary MicroRNA
- Más estrecho
RNA, Small Temporal
- Más estrecho
pre-miRNA
- Más estrecho
UI del concepto |
M0407989 |
Nota de alcance | Small double-stranded, non-protein coding RNAs, 21-25 nucleotides in length generated from single-stranded microRNA gene transcripts by the same RIBONUCLEASE III, Dicer, that produces small interfering RNAs (RNA, SMALL INTERFERING). They become part of the RNA-INDUCED SILENCING COMPLEX and repress the translation (TRANSLATION, GENETIC) of target RNA by binding to homologous 3'UTR region as an imperfect match. The small temporal RNAs (stRNAs), let-7 and lin-4, from C. elegans, are the first 2 miRNAs discovered, and are from a class of miRNAs involved in developmental timing. |
Término preferido | MicroRNAs |
Término(s) alternativo(s) |
Micro RNA MicroRNA RNA, Micro miRNA miRNAs |
UI del concepto |
M0507098 |
Nota de alcance | The RNA transcript of the miRNA genes prior to processing to pre-miRNA. |
Término preferido | Primary MicroRNA |
Término(s) alternativo(s) |
MicroRNA, Primary Primary miRNA miRNA, Primary pri miRNA pri-miRNA |
UI del concepto |
M0408369 |
Nota de alcance | A class of microRNAs that regulate developmental timing. |
Término preferido | RNA, Small Temporal |
Término(s) alternativo(s) |
Small Temporal RNA Temporal RNA, Small stRNA |
UI del concepto |
M0507502 |
Nota de alcance | Precursors to miRNA generated from pri-miRNA. They are exported from the nucleus where they are further processed by Dicer RNase to generate mature miRNA. |
Término preferido | pre-miRNA |
Término(s) alternativo(s) |
pre miRNA |
Queremos sus comentarios sobre el nuevo sitio web de DeCS / MeSH
Lo invitamos a completar una encuesta que no tomará más de 3 minutos.
Ir a la encuesta