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| Descriptor en español: |
Factor 3 Regulador del Interferón
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| Descriptor en inglés: | Interferon Regulatory Factor-3 | ||||||
| Descriptor en portugués: | Fator Regulador 3 de Interferon | ||||||
| Descriptor en francés: | Facteur-3 de régulation d'interféron | ||||||
| Término(s) alternativo(s): |
IFN Regulatory Factor 3 IFN-Regulatory Factor 3 IRF 3 Transcription Factor IRF-3 Transcription Factor Interferon Regulatory Factor 3 Transcription Factor, IRF-3 |
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| Código(s) jeráquico(s): |
D12.644.360.024.302.374 D12.776.157.057.050.374 D12.776.260.504.374 D12.776.476.024.385.374 D12.776.744.562 D12.776.930.332.374 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D050838 | ||||||
| Nota de alcance: | An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription. |
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| Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Nota Pública de MeSH: | 2006; INTERFERON REGULATORY FACTOR-3 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1996-2005 |
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| Nota de historia: | 2006(1996) |
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| Identificador de DeCS: | 50777 | ||||||
| ID del Descriptor: | D050838 | ||||||
| Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||||
| Fecha de establecimiento: | 01/01/2006 | ||||||
| Fecha de entrada: | 30/06/2005 | ||||||
| Fecha de revisión: | 23/11/2015 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Interferon Regulatory Factor-3
- Concepto preferido
| UI del concepto |
M0255479 |
| Nota de alcance | An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription. |
| Término preferido | Interferon Regulatory Factor-3 |
| Término(s) alternativo(s) |
IFN Regulatory Factor 3 IFN-Regulatory Factor 3 IRF 3 Transcription Factor IRF-3 Transcription Factor Interferon Regulatory Factor 3 Transcription Factor, IRF-3 |
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