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Descriptor en español: |
Securina
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Descriptor en inglés: | Securin | ||||
Descriptor en portugués: | Securina | ||||
Descriptor en francés: | Sécurine | ||||
Término(s) alternativo(s): |
PTTG Protein Pituitary Tumor Transforming Proteins Pituitary Tumor-Transforming Gene Protein Pituitary Tumor-Transforming Proteins |
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Código(s) jeráquico(s): |
D12.776.167.504 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D064249 | ||||
Nota de alcance: | Securin is involved in the control of the metaphase-anaphase transition during MITOSIS. It promotes the onset of anaphase by blocking SEPARASE function and preventing proteolysis of cohesin and separation of sister CHROMATIDS. Overexpression of securin is associated with NEOPLASTIC CELL TRANSFORMATION and tumor formation. |
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Calificadores permitidos: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Indexación anterior: |
Neoplasm Proteins (1997-2013) |
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Nota Pública de MeSH: | 2014; was indexed under NEOPLASM PROTEINS 1997-2013 |
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Nota de historia: | 2014 |
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Identificador de DeCS: | 55328 | ||||
ID del Descriptor: | D064249 | ||||
Documentos indizados en la Biblioteca Virtual de Salud (BVS): | Haga clic aquí para acceder a los documentos de la BVS | ||||
Fecha de establecimiento: | 01/01/2014 | ||||
Fecha de entrada: | 08/07/2013 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Securin
- Concepto preferido
UI del concepto |
M0580548 |
Nota de alcance | Securin is involved in the control of the metaphase-anaphase transition during MITOSIS. It promotes the onset of anaphase by blocking SEPARASE function and preventing proteolysis of cohesin and separation of sister CHROMATIDS. Overexpression of securin is associated with NEOPLASTIC CELL TRANSFORMATION and tumor formation. |
Término preferido | Securin |
Término(s) alternativo(s) |
PTTG Protein Pituitary Tumor Transforming Proteins Pituitary Tumor-Transforming Gene Protein Pituitary Tumor-Transforming Proteins |
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