Descripteur en français: | Sans traduction | ||||||
Descripteur en anglais: | Degrons | ||||||
Descripteur en espagnol: |
Degrones
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Descripteur en portugais: | Degrons | ||||||
Code(s) d'arborescence: |
G02.111.570.820.709.275.625 |
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Identificateur unique RDF: | https://id.nlm.nih.gov/mesh/D000097791 | ||||||
Note d'application: | Minimal elements within a protein that are sufficient for recognition and degradation by a proteolytic apparatus. Inherent degrons are comprised of short linear amino acid sequences and secondary protein structural features that increase the affinity to E3 LIGASE; and are involved in regulating the specificity and timing of PROTEIN DEGRADATION. Acquired degrons are mostly transient and conferred by post-translational modifications of specific amino acids within proteins. (From Mol Cell. 2016 Sep 15;63(6):1055-65) |
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Qualificatifs autorisés: |
DE effets des médicaments et des substances chimiques GE génétique IM immunologie PH physiologie RE effets des radiations |
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Identifiant DeCS: | 60652 | ||||||
ID du Descripteur: | D000097791 | ||||||
Documents indexés dans la Biblioteque Virtuelle de Santé (BVS): | Cliquez ici pour accéder aux documents VHL | ||||||
Date d'établissement: | 01/01/2024 | ||||||
Date d'entrée: | 26/07/2023 | ||||||
Date de révision: | 26/05/2023 |
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PHÉNOMÈNES ET PROCESSUS
Phénomènes chimiques [G02]Phénomènes chimiques
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