Visão selecionada em Inglês
Descritor em português: | Rianodina | ||||
Descritor em inglês: | Ryanodine | ||||
Descritor em espanhol: |
Rianodina
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Descritor em francês: | Ryanodine | ||||
Código(s) hierárquico(s): |
D02.455.849.291.686 D03.132.740 D03.383.129.578.805 |
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Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D012433 | ||||
Nota de escopo: | A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM. |
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Qualificadores permitidos: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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Número de registro: | 15662-33-6 | ||||
Nome CAS Tipo 1: | Ryanodol, 3-(1H-pyrrole-2-carboxylate) | ||||
Indexação Anterior: |
Alkaloids (1970-1974) |
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Nota MeSH pública: | 91; was see under ALKALOIDS 1975-90 |
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Nota histórica: | 91(75); was see under ALKALOIDS 1975-90 |
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Identificador DeCS: | 12805 | ||||
ID do descritor: | D012433 | ||||
Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||
Data de estabelecimento: | 01/01/1991 | ||||
Data de entrada: | 19/11/1974 | ||||
Data de revisão: | 31/05/2016 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Ryanodine
- Conceito preferido
Identificador do conceito |
M0019318 |
Nota de escopo | A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM. |
Termo preferido | Ryanodine |
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