Pesquisa
Descritor em português: Rianodina
Descritor em inglês: Ryanodine
Descritor em espanhol: Rianodina
Descritor rianodina
Nota de escopo: Metil-pirrol carboxilato de RYANIA que desestructura el CANAL DE LIBERACIÓN DE CALCIO DEL RECEPTOR DE RYANODINA para modificar la liberación de CALCIO del RETÍCULO SARCOPLÁSMICO que da lugar a alteración de la CONTRACCIÓN MUSCULAR. Se empleó previamente de modo experimental junto con TAPSIGARGINA y otros inhibidores de la recaptación de la ATPASA DEL CALCIO en el RETÍCULO SARCOPLÁSMICO.
Descritor em francês: Ryanodine
Código(s) hierárquico(s): D02.455.849.291.686
D03.132.740
D03.383.129.578.805
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D012433
Nota de escopo: A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
Qualificadores permitidos: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Número de registro: 15662-33-6
Nome CAS Tipo 1: Ryanodol, 3-(1H-pyrrole-2-carboxylate)
Indexação Anterior: Alkaloids (1970-1974)
Nota MeSH pública: 91; was see under ALKALOIDS 1975-90
Nota histórica: 91(75); was see under ALKALOIDS 1975-90
Identificador DeCS: 12805
ID do descritor: D012433
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1991
Data de entrada: 19/11/1974
Data de revisão: 31/05/2016
Ryanodine - Conceito preferido
Identificador do conceito M0019318
Nota de escopo A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
Termo preferido Ryanodine



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