Pesquisa
Descritor em português: Ressonância de Plasmônio de Superfície
Descritor em inglês: Surface Plasmon Resonance
Descritor em espanhol: Resonancia por Plasmón de Superficie
Descritor resonancia de plasmones de superficie
Nota de escopo: Técnica biosensora en que las biomoléculas capaces de enlazar con analitos o enlaces específicos son primero inmovilizadas en una cara de una película metálica. Entonces se proyecta luz por la cara opuesta de la película, para excitar los plasmones de superficie, o sea, las oscilaciones de los electrones libres propagándose a lo largo de la superficie de la película. Se mide el índice refractario de la luz que esta superficie refleja. Cuando las biomoléculas inmovilizadas son enlazadas por sus ligandos, se crea una alteración en los plasmones de superficie en la cara opuesta de la película, que es directamente proporcional al cambio en la masa enlazada o adsorbida. El enlace se mide por los cambios en el índice de refracción. La técnica se usa para estudiar las interacciones biomoleculares, como el enlace antígeno-anticuerpo.
Descritor em francês: Résonance plasmonique de surface
Termo(s) alternativo(s): Plasmon Resonance, Surface
Plasmon Resonances, Surface
Resonance, Surface Plasmon
Resonances, Surface Plasmon
Surface Plasmon Resonances
Código(s) hierárquico(s): E05.196.890
E05.601.043.700
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D020349
Nota de escopo: A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.
Nota de indexação: do not confuse with plasmon, extrachromosomal genetic material
Qualificadores permitidos: CL classification
EC economics
ES ethics
HI history
IS instrumentation
MT methods
SN statistics & numerical data
ST standards
TD trends
VE veterinary
Indexação Anterior: Biosensing Techniques (1991-1998)
Nota MeSH pública: 99
Nota histórica: 99
Identificador DeCS: 33868
ID do descritor: D020349
Classificação da NLM: QT 36.4
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1999
Data de entrada: 11/06/1998
Data de revisão: 23/06/2015
Surface Plasmon Resonance - Conceito preferido
Identificador do conceito M0029983
Nota de escopo A biosensing technique in which biomolecules capable of binding to specific analytes or ligands are first immobilized on one side of a metallic film. Light is then focused on the opposite side of the film to excite the surface plasmons, that is, the oscillations of free electrons propagating along the film's surface. The refractive index of light reflecting off this surface is measured. When the immobilized biomolecules are bound by their ligands, an alteration in surface plasmons on the opposite side of the film is created which is directly proportional to the change in bound, or adsorbed, mass. Binding is measured by changes in the refractive index. The technique is used to study biomolecular interactions, such as antigen-antibody binding.
Termo preferido Surface Plasmon Resonance
Termo(s) alternativo(s) Plasmon Resonance, Surface
Plasmon Resonances, Surface
Resonance, Surface Plasmon
Resonances, Surface Plasmon
Surface Plasmon Resonances



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