Visão selecionada em Inglês
| Descritor em português: | Alquilantes | ||||||
| Descritor em inglês: | Alkylating Agents | ||||||
| Descritor em espanhol: |
Alquilantes
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| Descritor em francês: | Agents alcoylants | ||||||
| Termo(s) alternativo(s): |
Agent, Alkylating Agents, Alkylating Alkylating Agent Alkylator Alkylators |
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| Código(s) hierárquico(s): |
D27.505.519.124 D27.888.569.035 |
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| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000477 | ||||||
| Nota de escopo: | Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. |
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| Qualificadores permitidos: |
AD administration & dosage AE adverse effects AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Nota MeSH pública: | 66 |
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| Nota histórica: | 66(64) |
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| Identificador DeCS: | 479 | ||||||
| ID do descritor: | D000477 | ||||||
| Classificação da NLM: | QV 269 | ||||||
| Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
| Data de estabelecimento: | 01/01/1966 | ||||||
| Data de entrada: | 01/01/1999 | ||||||
| Data de revisão: | 27/05/2020 |
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CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses -
CHEMICALS AND DRUGS
Chemical Actions and Uses [D27]Chemical Actions and Uses
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Alkylating Agents
- Conceito preferido
| Identificador do conceito |
M0000721 |
| Nota de escopo | Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. |
| Termo preferido | Alkylating Agents |
| Termo(s) alternativo(s) |
Agent, Alkylating Agents, Alkylating Alkylating Agent Alkylator Alkylators |
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