Pesquisa
Descritor em português: Fator 15 de Diferenciação de Crescimento
Descritor em inglês: Growth Differentiation Factor 15
Descritor em espanhol: Factor 15 de Diferenciación de Crecimiento
Descritor factor 15 de diferenciación del crecimiento
Termo(s) alternativo(s) GDF-15
Nota de escopo: Factor de diferenciación del crecimiento que se secreta en respuesta al estrés celular y en respuesta a la ACTIVACIÓN DE MACRÓFAGOS. Además, el factor 15 de diferenciación del crecimiento muestra una amplia gama de propiedades biológicas, como la inducción de formación de cartílago, la inhibición de la proliferación de progenitores hematopoyéticos y la inducción de la migración neuronal. 
Descritor em francês: Facteur-15 de croissance et de différenciation
Termo(s) alternativo(s): Differentiation Factor, Prostate
GDF-15
Macrophage Inhibitory Cytokine 1
Prostate Differentiation Factor
Código(s) hierárquico(s): D12.644.276.374.305
D12.644.276.954.300.915
D12.776.467.374.305
D12.776.467.942.300.915
D23.529.374.305
D23.529.942.300.915
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D055436
Nota de escopo: A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Nota MeSH pública: 2009; GROWTH DIFFERENTIATION FACTOR 15 was indexed under CYTOKINES 1997-2008
Nota histórica: 2009(1997)
Identificador DeCS: 53127
ID do descritor: D055436
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/2009
Data de entrada: 08/07/2008
Growth Differentiation Factor 15 - Conceito preferido
Identificador do conceito M0282507
Nota de escopo A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.
Termo preferido Growth Differentiation Factor 15
Termo(s) alternativo(s) Differentiation Factor, Prostate
GDF-15
Macrophage Inhibitory Cytokine 1
Prostate Differentiation Factor



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