Visão selecionada em Inglês
| Descritor em português: | Proteína Desglicase DJ-1 | ||||||
| Descritor em inglês: | Protein Deglycase DJ-1 | ||||||
| Descritor em espanhol: |
Proteína Desglicasa DJ-1
| ||||||
| Descritor em francês: | Protein deglycase DJ-1 | ||||||
| Termo(s) alternativo(s): |
DJ 1 PARK7 Protein DJ 1 Protein DJ-1 Protein DJ-1, Protein Deglycase DJ-1-PARK7 Protein DJ1 Protein Deglycase, Parkinsonism Associated PARK7 Protein Parkinson Protein 7 Parkinsonism Associated Deglycase |
||||||
| Código(s) hierárquico(s): |
D08.811.277.785 D12.776.705.875 |
||||||
| Identificador Único RDF: | https://id.nlm.nih.gov/mesh/D000071617 | ||||||
| Nota de escopo: | A protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, releasing repaired proteins and lactate or glycolate. It deglycates CYSTEINE, ARGININE and LYSINE residues to reactivate proteins by reversing glycation and prevent the formation of ADVANCED GLYCATION END PRODUCTS. It protects cells against OXIDATIVE STRESS and CELL DEATH by functioning as an oxidative stress sensor and redox-sensitive MOLECULAR CHAPERONE and PROTEASE. Mutations in the PARK7 gene are associated with autosomal-recessive, early-onset PARKINSON DISEASE. |
||||||
| Qualificadores permitidos: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
||||||
| Número de registro: | EC 3.1.2.- | ||||||
| Indexação Anterior: |
Intracellular Signaling Peptides and Proteins (1997-2016) Oncogene Proteins (1997-2016) |
||||||
| Nota MeSH pública: | 2017 |
||||||
| Nota histórica: | 2017 |
||||||
| Identificador DeCS: | 56493 | ||||||
| ID do descritor: | D000071617 | ||||||
| Documentos indexados na Biblioteca Virtual em Saúde (BVS): | Clique aqui para acessar os documentos da BVS | ||||||
| Data de estabelecimento: | 01/01/2017 | ||||||
| Data de entrada: | 08/07/2016 | ||||||
| Data de revisão: | 15/04/2016 |
-
-
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
|
Protein Deglycase DJ-1
- Conceito preferido
| Identificador do conceito |
M000615251 |
| Nota de escopo | A protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, releasing repaired proteins and lactate or glycolate. It deglycates CYSTEINE, ARGININE and LYSINE residues to reactivate proteins by reversing glycation and prevent the formation of ADVANCED GLYCATION END PRODUCTS. It protects cells against OXIDATIVE STRESS and CELL DEATH by functioning as an oxidative stress sensor and redox-sensitive MOLECULAR CHAPERONE and PROTEASE. Mutations in the PARK7 gene are associated with autosomal-recessive, early-onset PARKINSON DISEASE. |
| Termo preferido | Protein Deglycase DJ-1 |
| Termo(s) alternativo(s) |
DJ 1 PARK7 Protein DJ 1 Protein DJ-1 Protein DJ-1, Protein Deglycase DJ-1-PARK7 Protein DJ1 Protein Deglycase, Parkinsonism Associated PARK7 Protein Parkinson Protein 7 Parkinsonism Associated Deglycase |
Queremos a sua opinião sobre o novo sitio web do DeCS/MeSH
Convidamos-lhe a responder a uma pesquisa que não levará mais que 3 minutos
Ir para pesquisa
