Pesquisa
Descritor em português: Radicais Livres
Descritor em inglês: Free Radicals
Descritor em espanhol: Radicales Libres
Descritor radicales libres
Termo(s) alternativo(s) radical libre
Nota de escopo: Moléculas altamente reactivas con un electrón desapareado. Los radicales libres se generan en procesos normales y patológicos. Los radicales libres incluyen las especies reactivas de oxígeno y nitrógeno (RONS, por sus siglas en inglés). Son agentes presuntos o confirmados de daño tisular en circunstancias muy diversas, entre otras las radiaciones, la exposición a agentes químicos del entorno y el envejecimiento. Se está investigando activamente la prevención natural y farmacológica del daño por radicales libres.
Descritor em francês: Radicaux libres
Termo(s) alternativo(s): Free Radical
Radical, Free
Radicals, Free
Código(s) hierárquico(s): D01.339
D02.389
Identificador Único RDF: https://id.nlm.nih.gov/mesh/D005609
Nota de escopo: Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. Free radicals include reactive oxygen and nitrogen species (RONS). They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.
Nota de indexação: IM GEN only; usually NIM with coord IM
Qualificadores permitidos: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Indexação Anterior: Chemistry (1966)
Chemistry, Physical (1966)
Electron Spin Resonance (1966)
Nota MeSH pública: 76
Nota histórica: 76(67)
Veja também os descritores: Free Radical Scavengers MeSH
Spin Trapping MeSH
Identificador DeCS: 5744
ID do descritor: D005609
Documentos indexados na Biblioteca Virtual em Saúde (BVS): Clique aqui para acessar os documentos da BVS
Data de estabelecimento: 01/01/1976
Data de entrada: 01/01/1999
Data de revisão: 27/05/2020
Free Radicals - Conceito preferido
Identificador do conceito M0008827
Nota de escopo Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. Free radicals include reactive oxygen and nitrogen species (RONS). They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.
Termo preferido Free Radicals
Termo(s) alternativo(s) Free Radical
Radical, Free
Radicals, Free



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